Results 131 to 140 of about 302,337 (268)

Acute Severe Ulcerative Colitis: An International Delphi Consensus on Clinical Trial Design and Endpoints

Sailish Honap, Vipul Jairath, Bruce E. Sands, Parambir S. Dulai, Peter Higgins, Peter De Cruz, Ana Gutiérrez, Paulo Gustavo Kotze, Byong Duk Ye, Taku Kobayashi, Richard B. Gearry, Pablo A. Olivera, Aurélien Amiot, Mahmoud Mosli, Sameer Al Awadhi, Jonas Halfvarson, Kamal Patel, Shaji Sebastian, Silvio Danese, Laurent Peyrin-Biroulet   +19 more
openalex   +1 more source

Measuring the Impact of the Substitution of Innovator Biologics With Biosimilars on Uptake and Costs Among Ontario Public Drug Benefit Recipients

Clinical Pharmacology &Therapeutics, EarlyView.
In Ontario, biologics have historically represented a small proportion of public drug claims but a large proportion of spending. Biosimilars, lower cost alternatives to biologics, offer a potential solution to the rising spending on biologics. From March 2023 to January 2024, the Ontario Ministry of Health required public drug program beneficiaries on ...
Anita Iacono, Martin K. H. Ho, Joanna Yang, Tonya Campbell, William Wynne, Dana Shearer, Lene Andersen, Eric Majer, Shaleesa Ledlie, Mina Tadrous, Tara Gomes   +10 more
wiley   +1 more source

Antispasmodic and Anti-inflammatory Effects of Kratom Leaf Extract on Acetic Acid-induced Ulcerative Colitis in Mice. [PDF]

In Vivo
Pradab S, Yupanqui CT, Tipbunjong C, Hayeeawaema F, Sengnon N, Wungsintaweekul J, Khuituan P.   +6 more
europepmc   +1 more source

Kag-308, a Novel Orally Active EP4 Agonist, Ameliorates Mucosal Injury on Endoscopic Examination in a Chronic Colitis Model

, 2011
Tango Handa, Masahiro Amakawa, Yoshihide Miyake, Mihoko Takami, Tatsunori Murata, Katsuhiko Konishi, Yasushi Matsumura   +6 more
openalex   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Protective Effects of Betanin in Acute and Subacute Periods in Experimental Colitis Induced by Trinitrobenzene Sulfonic Acid. [PDF]

Nutrients
Taskiran I, Keskin A, Coskun A, Sirinyildiz F, Meteoglu I.   +4 more
europepmc   +1 more source

NOTES ON CASES OF MUCOUS COLITIS TREATED WITH CHARCOAL.

, 1918
T.B. Broadway
openalex   +2 more sources

Loss of p27Kip1 leads to expansion of CD4+ effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of Smad4 [PDF]

, 2020
Sung Hee Choi, Emily C. Barker, Kyle J. Gerber, John J. Letterio, Byung‐Gyu Kim   +4 more
openalex   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

The TAAR1 antagonist EPPTB ameliorates colitis via serotonin inhibition. [PDF]

Biochem Biophys Rep
Luo L, Zhang T, Liang L, Chen W, Wang T, Chen W, Xiao H, Zhang G.   +7 more
europepmc   +1 more source