Results 171 to 180 of about 672,024 (402)

All Nanozyme‐Based Cascade Reactions for Biomedical Applications: from Self‐Cascading Nanozyme to Immobilized Cascade Nanozyme

open access: yesAdvanced Science, EarlyView.
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu   +4 more
wiley   +1 more source

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system. [PDF]

open access: yes, 2019
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Akiba, Yasutada   +2 more
core  

Infliximab for induction and maintenance therapy for ulcerative colitis.

open access: yesNew England Journal of Medicine, 2005
P. Rutgeerts   +13 more
semanticscholar   +1 more source

Research Progress on Idebenone in Neurodegenerative Diseases

open access: yesAGING MEDICINE, EarlyView.
The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang   +10 more
wiley   +1 more source

Ground flaxseed reverses protection of a reduced-fat diet against Citrobacter rodentium-induced colitis [PDF]

open access: bronze, 2018
Pekka Määttänen   +12 more
openalex   +1 more source

Mechanism of Sishen-Pill-Regulated Special Memory T and mTfh Cell via Involving JAK/STAT5 Pathway in Colitis Mice [PDF]

open access: hybrid, 2022
Mengxue Wang   +7 more
openalex   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

RPSLearner: A Novel Approach Based on Random Projection and Deep Stacking Learning for Categorizing Non‐Small Cell Lung Cancer

open access: yesAdvanced Intelligent Systems, EarlyView.
Identifying non‐small cell lung cancer (NSCLC) subtypes is essential for precision cancer treatment. Conventional methods are laborious, or time‐consuming. To address these concerns, RPSLearner is proposed, which combines random projection and stacking ensemble learning for accurate NSCLC subtyping. RPSLearner outperforms state‐of‐the‐art approaches in
Xinchao Wu, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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