Results 31 to 40 of about 309,460 (288)

Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice

Anemia, 2015
Current iron supplementation practice in geriatric patients is erratic and lacks evidence-based recommendations. Despite potential benefits in this population, intravenous iron supplementation is often withheld due to concerns regarding pharmacy expense,
Matthias Bach, Tabea Geisel, Julia Martin, Bettina Schulze, Roland Schaefer, Garth Virgin, Juergen Stein   +6 more
doaj   +1 more source

Association between anti-tumor necrosis factor alpha exposure and new-onset autoimmune diseases in inflammatory bowel disease: a nationwide case-control study in Korea [PDF]

Intestinal Research
Background/Aims Autoimmune-related events following anti-tumor necrosis factor alpha (anti-TNF-α) therapy are increasingly reported, but population-level data on new-onset autoimmune disease in inflammatory bowel disease (IBD) remain limited.
Shin Ju Oh, Ji Eun Kim, Su Jin Jeong, Chang Kyun Lee, the Big Data Research Group (BDRG) of the Korean Society of Gastroenterology   +4 more
doaj   +1 more source

Safety and Efficacy of Ustekinumab in the Treatment of Crohn Disease: A Systematic Review and Meta-analysis

Journal of Coloproctology, 2022
Background and Aims The present systematic review and meta-analysis was designed to estimate the safety and effectiveness of ustekinumab in the treatment of Crohn disease (CD) in clinical trials and observational studies.
Mohammed Assem Khorshid, Ahmed Cordie, Sherief Abd-Elsalam   +2 more
doaj   +1 more source

An Etiologic Profile of Anemia in 405 Geriatric Patients

Anemia, 2014
Background. Anemia is a common condition in the elderly and a significant risk factor for increased morbidity and mortality, reducing not only functional capacity and mobility but also quality of life.
Tabea Geisel, Julia Martin, Bettina Schulze, Roland Schaefer, Matthias Bach, Garth Virgin, Jürgen Stein   +6 more
doaj   +1 more source

Incidence and Prevalence of Microscopic Colitis between 2001 and 2016:A Danish Nationwide Cohort Study

, 2020
Background and Aims: Epidemiological studies suggest an increasing global incidence of microscopic colitis, including collagenous colitis and lymphocytic colitis.
Løkkegaard, Ellen Christine Leth, Bonderup, Ole Kristian, Lokkegaard, Ellen Christine Leth,, Weimers, Petra,, Lophaven, Soren,, Ankersen, Dorit Vedel, Lophaven, Søren, Weimers, Petra, Munkholm, Pia,, Münch, Andreas, Ankersen, Dorit Vedel,, Münch, Andreas,, Burisch, Johan, Munkholm, Pia, Bonderup, Ole K.,, Burisch, Johan,   +15 more
core   +1 more source

DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]

, 2014
Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Winter, Harland, Szigeti, Reka, Kaplan, Jess L., Harris, R. Alan, Nagy-Szakal, Dorottya, Kellermayer, Richard, Ferry, George D., Opekun, Antone, Bronsky, Jiri, Mir, Sabina A.V., Frank, Eibe   +10 more
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Impaired Long-Term Quantitative Cellular Response to SARS-CoV-2 Vaccine in Thiopurine-Treated IBD Patients

Cells
Background: Studies investigating the long-term cellular immune response to SARS-CoV-2 mRNA vaccines in patients with inflammatory bowel disease (IBD) remain limited, particularly among those receiving immunosuppressive therapy. Methods: We prospectively
Luis Mayorga Ayala, Claudia Herrera-deGuise, Juliana Esperalba, Xavier Martinez-Gomez, Elena Céspedes Martinez, Xavier Serra Ruiz, Virginia Robles, Ernesto Lastiri, Zahira Perez, Elena Oller, Candela Fernandez-Naval, Mónica Martinez-Gallo, Francesc Casellas, Natalia Borruel   +13 more
doaj   +1 more source

The Establishment of a National Tissue Bank for Inflammatory Bowel Disease Research in Canada

Canadian Journal of Gastroenterology, 2003
The Crohn’s and Colitis Foundation of Canada (CCFC) has established a national bank for tissue, serum and blood from patients with inflammatory bowel disease (IBD).
Stephen M Collins, Kevin McHugh, Ken Croitoru, Micheal Howorth   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source