Results 61 to 70 of about 321,837 (258)

Patient-Reported Outcomes Are a Practical Tool for Monitoring Crohn’s Disease Activity in Real-World Care

Gastro Hep Advances
Background and Aims: Crohn’s disease activity scores are used to “quantify” disease activity, for clinical care, and research. They can be impractical to use repeatedly in busy clinical settings.
Wai Kin Su, Susan J. Connor, Jane M. Andrews, William Wilson   +3 more
doaj   +1 more source

Metagenomic Characterization of Microbial Communities In Situ Within the Deeper Layers of the Ileum in Crohn’s DiseaseSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Microbial dysbiosis and aberrant host–microbe interactions in the gut are believed to contribute to the development and progression of Crohn’s disease (CD).
Chandra Sekhar Pedamallu, Ami S. Bhatt, Susan Bullman, Sharyle Fowler, Samuel S. Freeman, Jacqueline Durand, Joonil Jung, Fujiko Duke, Veronica Manzo, Diana Cai, Ashwin Ananthakrishnan, Akinyemi I. Ojesina, Aruna Ramachandran, Dirk Gevers, Ramnik J. Xavier, Atul K. Bhan, Matthew Meyerson, Vijay Yajnik   +17 more
doaj   +1 more source

The Effect of Vitamin D on Intestinal Inflammation and Faecal Microbiota in Patients with Ulcerative Colitis [PDF]

, 2018
This work was supported by the European Crohn’s and Colitis Organisation Fellowship awarded to Dr Mayur Garg, and St Mark’s Foundation Research Grant 2015 awarded to Prof Ailsa Hart and Dr Mayur Garg.Peer ...
Sophie Shaw, Garg, Mayur, Ding, John Nik, Mayur Garg, Hold, Georgina, Ailsa Hart, Hart, Ailsa, Philip Hendy, Hendy, Philip, John Nik Ding, Shaw, Sophie, Georgina Hold   +11 more
core   +1 more source

Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman, Mei Li, Xiudong Lei, Hui Zhao, Juan I. Ruiz, Sharon H. Giordano, Alexis R. Ogdie, Maria E. Suarez‐Almazor   +7 more
wiley   +1 more source

Gut microbial and human genetic signatures of inflammatory bowel disease increase risk of comorbid mental disorders

npj Genomic Medicine
The high prevalence of comorbid mental disorders (CMDs) in patients with inflammatory bowel disease (IBD) is well-documented. This study delves into the intricate CMD-IBD relationship through comprehensive analyses using human variants, gut microbiome ...
Junho Lee, Shin Ju Oh, Eunji Ha, Ga Young Shin, Hyo Jong Kim, Kwangwoo Kim, Chang Kyun Lee   +6 more
doaj   +1 more source

Lactobacillus Intestinalis Primes Epithelial Cells to Suppress Colitis‐Related Th17 Response by Host‐Microbe Retinoic Acid Biosynthesis

Advanced Science, 2023
Gut microbiome is integral to the pathogenesis of ulcerative colitis. A novel probiotic Lactobacillus intestinalis (L. intestinalis) exerts a protective effect against dextran sodium sulfate‐induced colitis in mice.
Qi‐Wen Wang, Ding‐Jia‐Cheng Jia, Jia‐Min He, Yong Sun, Yun Qian, Qi‐Wei Ge, Ya‐Dong Qi, Qing‐Yi Wang, Ying‐Ying Hu, Lan Wang, Yan‐Fei Fang, Hui‐Qin He, Man Luo, Li‐Jun Feng, Jian‐Min Si, Zhang‐Fa Song, Liang‐Jing Wang, Shu‐Jie Chen   +17 more
doaj   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Smoking is Associated with an Increased Risk of Microscopic Colitis: Results From Two Large Prospective Cohort Studies of US Women

, 2018
Introduction: Long-term data on the influence of smoking on risk of microscopic colitis are limited. We therefore sought to examine and characterize the association between smoking and risk of incident microscopic colitis in two large prospective cohorts
Kristin E Burke, Andrew T Chan, Chan, Andrew T.,, Lochhead, Paul,, Hamed Khalili, Olen, Ola,, Richter, James M.,, Ludvigsson, Jonas F.,, Ola Olen, Ashwin N Ananthakrishnan, Burke, Kristin E.,, Jonas F Ludvigsson, Paul Lochhead, Ananthakrishnan, Ashwin N.,, James M Richter, Khalili, Hamed,, Lochhead, P, Richter, JM, Khalili, H, Chan, AT, Burke, KE, Olen, O, Ananthakrishnan, AN, Ludvigsson, JF   +23 more
core   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]

, 2002
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Török, H.-P., Hoelscher, Michael, Folwaczny, Christian, Vilsmaier, F., Herbinger, K. H., Glas, J.   +5 more
core   +1 more source