Results 41 to 50 of about 177,850 (297)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The effectiveness of thermochemistry’s ludo game media for improving students’ learning outcomes and collaboration skills

Jurnal Inovasi dan Teknologi Pembelajaran
This study measured the effectiveness of using Ludo game media on thermochemistry on students’ learning outcomes and collaboration skills. This study used a group pretest-posttest design with a purposive sampling technique involving class XI-2 with 33 ...
Anna Jurniar, Stephani Yunita Siahaan
doaj   +1 more source

Does student's critical thinking and collaboration skills can empower through investigation and thinking learning strategy?

JPBI (Jurnal Pendidikan Biologi Indonesia), 2023
The low critical thinking skills and collaboration skills of students in biology learning are caused by the dominance of conventional learning, so they require alternative learning strategies.
Lina Listiana, Nadiya Mutiara Loka, Yuni Gayatri   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

STEM e-worksheet innovation: Encouraging collaboration in excretory system learning

Biosfer
Excessive use of gadgets leads to individualism and less exploration and thinking among students due to the easiness offered by the gadgets. Moreover, students have low collaboration skills so that less able to cooperate. The study aims to produce a STEM-
Anisa Minatani, Supriyatin Supriyatin, Rusdi Rusdi   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The Effect of Outdoor Study-Based Experiential Learning Model on the Collaborative Ability of High School Geography Students

Jurnal Pendidikan Geografi Undiksha
Conventional learning models have proven to be less than optimal, so a solution is needed using the Experiential Learning model with the outdoor study method.
Defita Dwi Anggraeni, Sri Astutik, Era Iswara Pangastuti, Ana Susiati, Kurnia Maulidi Noviantoro   +4 more
doaj   +1 more source

Development of design collaboration skills

Journal of Engineering Design, 2012
This paper aims to advance our conceptual understanding of design collaboration, a domain-specific subset of collaboration skills that emphasises knowledge-sharing and knowledge-integration processes. This paper explores how design collaboration skills develop along with design expertise across three stages of experience.
Kleinsmann, M., Deken, F., Dong, A., Lauche, K.   +3 more
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source