Results 41 to 50 of about 687,512 (255)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Community-based participatory research and integrated knowledge translation: advancing the co-creation of knowledge

Implementation Science, 2017
Background Better use of research evidence (one form of “knowledge”) in health systems requires partnerships between researchers and those who contend with the real-world needs and constraints of health systems.
Janet Jull, Audrey Giles, Ian D. Graham
doaj   +1 more source

Distinguishing knowledge-sharing, knowledge-construction, and knowledge-creation discourses [PDF]

, 2009
The study reported here sought to obtain the clear articulation of asynchronous computer-mediated discourse needed for Carl Bereiter and Marlene Scardamalia's knowledge-creation model.
van Aalst, J
core   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

The Wisdom of Collaborative Network Organizations: Capturing the Value of Networked Individuals

Prometheus, 2008
Digital networks, particularly the Internet, are used widely to search for information and to share expertise and knowledge between peers. Such collaborative problem solving and co‐creation of services and products go beyond traditional organizational ...
William H. Dutton
doaj   +1 more source

Manifesto sprint on biocultural diversity: an experimental approach to knowledge co-creation, discourse design and collaborative writing

Cogent Arts & Humanities, 2022
New methodological and co-creation approaches are needed in Digital Humanities (DH) for cross-disciplinary collaboration oriented to sustainability. More specifically—in the context of Environmental Humanities and regarding biocultural diversity—a key ...
Enric Senabre Hidalgo, Albin Wagener, Eveline Wandl-Vogt, Robert Lew   +3 more
doaj   +1 more source

Assessment of co-creativity in the process of game design [PDF]

, 2019
We consider game design as a sociocultural and knowledge modelling activity, engaging participants in the design of a scenario and a game universe based on a real or imaginary socio-historical context, where characters can introduce life narratives and ...
Arnab, Sylvester, Minoi, Jacey Lynn, Mohamad, Fitri, Morini, L., Romero, Margarida, Smet, Cindy De   +5 more
core   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Co-creation as open innovation and its impact on environmental performance: Comparative insights from university and vocational students

Journal of Open Innovation: Technology, Market and Complexity
This study addresses the urgent need for innovative solutions to environmental issues by focusing on youth development within educational institutions, which play a crucial role in fostering environmentally conscious behaviors.
Siraphat Padthar, Chavis Ketkaew
doaj   +1 more source

The roles of gamification, knowledge creation, and entrepreneurial orientation towards firm performance

International Journal of Innovation Studies, 2022
In a highly competitive industry, it has been a best practice that dynamic capabilities guide technology firms to cope with challenging situations. Meanwhile, knowledge creation enables the firm to condition the success and continuity of innovations ...
Elidjen, Desman Hidayat, Edi Abdurachman   +2 more
doaj   +1 more source