Results 191 to 200 of about 1,136,104 (305)

From the Guest Editors: Artificial Intelligence and Big Data in the Health Sciences. [PDF]

Dela J Public Health
Shi W, Deng Y.
europepmc   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

The Evolving Role of AI in Simulation-Based Medical Education: A Narrative Review. [PDF]

Adv Med Educ Pract
Hasan S, Ahmed A, Ismail FW.
europepmc   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Computational renaissance in herbal medicine: A 20-year bibliometric deciphering of molecular dynamics simulations reshaping traditional Chinese medicine drug discovery. [PDF]

Saudi Pharm J
Ye L, Liu Y, Peng X, He M.
europepmc   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Systems leadership for quality in health care: from principles to actions. [PDF]

Int J Qual Health Care
Saxena A, Dickson G, Engel C, Agarwal V, Ahmed Z, Armit K, Braithwaite J, Dickson S, Lachman P, Moffat-Bruce S, Shaikh U, Wiig S.   +11 more
europepmc   +1 more source

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

Advanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu, Mengsi Zhan, Haoyu Huang, Jianhong Wang, Cheng Ni, Xiaojun Zhou, Hannah Küttner, Cong Song, Xiangyang Shi, Andrij Pich   +9 more
wiley   +1 more source

Tracing Sub‐Monolayer Contamination on Wafer‐Scale 2D Materials

Advanced Functional Materials, EarlyView.
Sub‐monolayer adventitious carbon contamination limits the performance and reproducibility of 2D material‐based devices. This study demonstrates scanning helium microscopy (SHeM) as a non‐destructive, ultra‐sensitive tool for wafer‐scale imaging of surface cleanliness.
Chenyang Zhao, Sam M. Lambrick, Ke Wang, Shaoliang Guan, Aleksandar Radić, David J. Ward, Andrew P. Jardine, Boyao Liu   +7 more
wiley   +1 more source

Brain health care accelerator: A primary care-centered model for scaling dementia diagnosis and care. [PDF]

Alzheimers Dement
Burns JM, Morris JK, Vidoni ED, Townley RA, Gillen LR, Smith TR, Jones JE, Nelson MB, Mudaranthakam DP, Perales-Puchalt J, Lewandowski T, Niedens CM, Parks AC, Brunette AM, Aschenbrenner AJ, Bucy TI, Forcino RC, Woodward JL.   +17 more
europepmc   +1 more source