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Burns are soft tissue injuries that require particular care for wound healing. Current tissue engineering approaches are aimed at identifying the most efficient treatment combinations to restore the tissue properties and function by using adapted ...
Sorina Dinescu+9 more
doaj +1 more source
Recent progresses of collagen dressings for chronic skin wound healing
The skin plays a fundamental role in regulating the body’s internal balance and protecting against external traumas. A broad variety of environmental risk factors frequently result in acute skin wounds, whose inappropriate treatments would lead to ...
Shuangni Shi+4 more
doaj +1 more source
Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]
Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Dandurand, Jany+7 more
core +2 more sources
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
Guided bone regeneration in long-bone defect with a bilayer mineralized collagen membrane
Bone regeneration for large, critical-sized bone defects remains a clinical challenge nowadays. Guided bone regeneration (GBR) is a promising technique for the repair of multiple bone defects, which is widely used in oral and maxillofacial bone defects ...
Fuli Peng+14 more
doaj +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
INTRODUCTION. Indomethacin is a derivative of indoleacetic acid and has anti-inflammatory, analgesic and antipyretic effects. However, the results of numerous studies show that indomethacin, like many other nonsteroidal anti-inflammatory drugs (NSAIDs ...
Pavel A. Markov+5 more
doaj +1 more source
AbstractThe extracellular matrix is often defined as the substance that gives multicellular organisms (from plants to vertebrates) their structural integrity, and is intimately involved in their development. Although the general functions of extracellular matrices are comparable, their compositions are quite distinct.
Robert Garrone+3 more
openaire +3 more sources
Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. [PDF]
Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and many human disorders, including pathological tissue fibrosis in major organs.
Bai, Meirong+12 more
core +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source