Results 81 to 90 of about 1,026 (135)

Targeting cancer matrix mechanics: fibronectin fiber relaxation correlates with ADAM8 expression in PDAC and is amenable to in vitro modulation

Frontiers in Biophysics
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancers, characterized by a dense desmoplastic stroma rich in extracellular matrix (ECM) that impairs therapy and promotes tumor progression. Fibronectin (FN), a major ECM component, provides
Konstantin M. P. Wolf, Lea S. Ottenwald, Martin Wartenberg, Mamta Chabria, Viola Vogel   +4 more
doaj   +1 more source

CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma

BMC Oral Health
Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high mortality, and poor prognosis.
Zhichao Zhang, Xusheng Ren, Yiling Wang, Ping Liu, Peng Lin, Shumei Jin, Chao Xu   +6 more
doaj   +1 more source

Persistence of alveolar fibroblast-derived ADAMTS4+ cells in a preclinical model of delayed pulmonary fibrosis resolution. [PDF]

Nat Commun
Zabihi M, Khadim A, Lingampally A, Vazquez-Armendariz AI, Hadzic S, Panagiotidis GD, Kalina D, Halweg J, Procida-Kowalski T, Bartkuhn M, Chu X, Koepke J, Samakovlis C, Boehm M, Weissmann N, Günther A, Seeger W, Braubach P, Herold S, Wygrecka M, Bellusci S, El Agha E.   +21 more
europepmc   +1 more source

Proteograph™-based proteome and sphingolipidome analyses identified novel serum biomarkers to monitor astronauts' health in spaceflight. [PDF]

Front Physiol
Moriggi M, Capitanio D, Torretta E, Metatla I, Frings-Meuthen P, Heinz V, Trautmann G, Salanova M, Blottner D, Gelfi C.   +9 more
europepmc   +1 more source

Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer. [PDF]

Oncotarget
Duval H, Toomey B, Karam M, Braun T, Fournier D, Grant C, Fairfield H, Chepurko V, Chepurko E, Schimelman A, Nestor B, Ryzhov S, Lindner V, Reagan MR.   +13 more
europepmc   +1 more source

Meox1 Promotes Cardiac Fibrosis and Pathological Remodeling following Myocardial Infarction through Cthrc1/p-Smad2/3 Signaling. [PDF]

Int J Biol Sci
Zhang M, Meng XW, Yang YF, Chen XY, Wang YC, Wan JJ, Ding J, Wang BY, Peng K, Ji FH.   +9 more
europepmc   +1 more source

Rapid bone formation and remodeling via vascular infiltration of a hydroxyapatite/collagen nanocomposite beneath the calvarial periosteum. [PDF]

Biomater Biosyst
Arai H, Uezono M, Kikuchi M, Amano H, Derong C, Aoki K, Moriyama K.   +6 more
europepmc   +1 more source

TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15. [PDF]

Proc Natl Acad Sci U S A
Shyer JA, Wehbe F, Davidson CD, Bender HS, Thai M, Cox C, Missarova A, Arlantico A, Hall B, Zhang R, Kim D, Altieri A, Hasan S, Namdar A, Chen T, Hakim SW, Guidos C, Brightbill HD, Kuo T, Heimberg G, Corrada Bravo H, Ratsimandresy RA, Uttarwar S, Teng G, Salem O, Arjomandi M, Wilson MS, Darmanis S, Ziai J, Scherl A, Modrusan Z, Wolters PJ, Buechler MB, Vander Heiden JA, Turley SJ.   +34 more
europepmc   +1 more source

LRP1 activated by AT2 cell-secreted MDK inhibits fibrotic ferroptosis in idiopathic pulmonary fibrosis. [PDF]

iScience
Hua W, Wang Z, Dai Z, Zhang Z, Li X, Wu B, Huang M, Chen J.   +7 more
europepmc   +1 more source