Results 71 to 80 of about 1,026 (135)

Long non-coding RNA NONMMUG014387 promotes Schwann cell proliferation after peripheral nerve injury

Neural Regeneration Research, 2017
Schwann cells play a critical role in peripheral nerve regeneration through dedifferentiation and proliferation. In a previous study, we performed microarray analysis of the sciatic nerve after injury.
Bin Pan, Zhong-ju Shi, Jia-yin Yan, Jia-he Li, Shi-qing Feng   +4 more
doaj   +1 more source

Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signalingResearch in context

EBioMedicine, 2019
Background: Hepatic fibrosis is caused by chronic liver injury and may progress toward liver cirrhosis, and even hepatocellular carcinoma. However, current treatment is not satisfactory.
Jun Li, Yahui Wang, Mingze Ma, Shuheng Jiang, Xueli Zhang, Yanli Zhang, Xiaomei Yang, Chunjie Xu, Guangang Tian, Qing Li, Yang Wang, Lei Zhu, Huizhen Nie, Mingxuan Feng, Qiang Xia, Jianren Gu, Qing Xu, Zhigang Zhang   +17 more
doaj   +1 more source

Serum Collagen Triple Helix Repeat Containing-1 Levels are Related to Radiological Affection and Disease Activity in Rheumatoid Arthritis

Open Access Rheumatology: Research and Reviews, 2022
Eman Mostafa Nassef,1 Hemmat Ahmed Elabd,2 Hala Mohamed Elzomor,2 Basma Mohamed Mohamed Ali El Nagger,2 Amira Shahin Ibrahim,2 Amal Hussein Ibrahim,1 Hend Gamal Kotb,1 Donia Ahmed Hassan,3 Rasha Elsayed Mohamed Abd ElAziz,4 Eman El Sayed Mohamed3 ...
Nassef EM, Elabd HA, Elzomor HM, El Nagger BMMA, Ibrahim AS, Ibrahim AH, Kotb HG, Hassan DA, Abd ElAziz REM, Mohamed EES   +9 more
doaj  

CTHRC1 drives megakaryocyte-mediated immunotherapy resistance in esophageal squamous cell carcinoma via the integrin αIIbβ3/Rap1 pathway and is targetable by mRNA vaccination

Molecular Cancer
The clinical efficacy of immunotherapy in advanced esophageal squamous cell carcinoma (ESCC) remains suboptimal, as most patients eventually develop drug resistance and experience disease progression.
Yixin Liu, Jianfeng Zhou, Mengyuan Song, Jian Wang, Qixin Shang, Jiajia Du, Yanxin Li, Xiangzheng Chen, Jing Wang, Xuerui Liao, Longqi Chen, Weimin Li, Yong Yuan, Yushang Yang, Yangping Wu   +14 more
doaj   +1 more source

microRNA-134 inhibits melanoma growth and metastasis by negatively regulating collagen triple helix repeat containing-1 (CTHRC1).

International journal of clinical and experimental pathology
Melanoma, a malignant tumor of melanocytes, is considered to be the most aggressive of skin cancers and its incidence keeps increasing worldwide. miR-134 and CTHRC1 have been demonstrated to be involved in the occurrence and development of various tumors. However, their roles are still elusive in the progression of melanoma.
Yuan, Li, Yong, Fu, Yu, Gao, Haiying, Li, Lei, Ma, Chunmen, Shu, Na, Li, Chong, Ma   +7 more
openaire   +1 more source

CTHRC1: An Emerging Hallmark of Pathogenic Fibroblasts in Lung Fibrosis

Cells
Pulmonary fibrosis is a chronic, progressive, irreversible lung disease characterized by fibrotic scarring in the lung parenchyma. This condition involves the excessive accumulation of extracellular matrix (ECM) due to the aberrant activation of ...
Zhussipbek Mukhatayev, Altynay Adilbayeva, Jeannette Kunz   +2 more
doaj   +1 more source

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

Potential value of collagen triple helix repeat containing-1 (CTHRC1) in systemic lupus erythematosus (SLE) patients with arthritis detected clinically or by musculoskeletal ultrasound

The Egyptian Rheumatologist, 2023
Reem El-Mallah, Dina A. Farrag, Nesma Ahmed Safwat   +2 more
openaire   +1 more source

Collagen triple helix repeat-containing 1 protein: an emerging biomarker and its influence on the clinical and sonographic disease severity in Egyptian medicated female rheumatoid arthritis patients

Egyptian Rheumatology and Rehabilitation
Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of synovial joints, with a multifactorial etiology. Collagen triple helix repeat-containing 1 protein (CTHRC1) is a biomarker produced by fibroblast-like synoviocytes ...
Shaden Essam, Diaa Fahmy Mohasseb, Noha A. Elsawy, Neveen Lewis Mikhael Saad, Yousra Hisham Abdel-Fattah   +4 more
doaj   +1 more source

Identification of CTHRC1 as a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma by Bioinformatics Analysis

Translational Oncology
Background: Esophageal squamous cell carcinoma (ESCC) carries one of the highest case-fatality rates among gastrointestinal malignancies, owing in part to the scarcity of molecularly validated prognostic indicators.
Shuoguoli Li, Yongan Kang, Yijun Qi
doaj   +1 more source