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Conformational selection and collagenolysis in Type III collagen

Proteins: Structure, Function, and Bioinformatics, 2009
AbstractMatrix metalloproteases (MMPs) cleave native collagen at a single site despite the fact that collagen contains more than one scissile bond that can, in principle, be cleaved. For peptide bond hydrolysis to occur at one specific site, MMPs must (1) localize to a region near the unique scissile bond, (2) bind residues at the catalytic site that ...
Ramon, Salsas-Escat, Collin M, Stultz
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Studies on the sulfhydryl groups in type III collagen

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1976
The Type III collagen molecule, [alpha](III)]3, is comprised of three alphal(III) chains each of which contains two cysteinyl residues. Free sulfhydryl groups, however, could not be detected in the denatured, trimeric gamma-component of Type III collagen as judged by the failure to form derivatives with the alkylating reagents iodo-[14C]acetic acid and
M, Schneir, E J, Miller
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Role of type III collagen in bladder filling

Neurourology and Urodynamics, 1998
The function of the urinary bladder is to store urine at low pressure and expel it periodically. To accomplish this, it must have the appropriate structural properties to accommodate slow but continuous volume changes. While much is presently known about the functional measurements of compliance, relatively little is known about the structural basis of
S L, Chang   +3 more
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Bovine dental pulp collagens: Characterization of types III and V collagen

Archives of Oral Biology, 1990
Pulp was essentially solubilized by partial pepsin digestion. The various genetic types of collagens were isolated by differential salt precipitation and extraction. Types I, III and V collagen represented 56, 41 and 2% of the total collagen, respectively. The type V collagen comprised two different molecular species consisting of [alpha 1(V)]2 alpha 2(
M, Tsuzaki, M, Yamauchi, G L, Mechanic
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Collagen type III glomerulopathy: a new type of hereditary nephropathy

Pediatric Nephrology, 1993
A new type of hereditary glomerulopathy was observed in ten children presenting with early and progressive glomerular symptoms, often associated with hypertension. Light microscopy showed a diffuse increase in the mesangial matrix and generalized widening of the capillary walls.
M C, Gubler   +6 more
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Influence of Fibronectin on the Fibrillogenesis of Type I and Type III Collagen

Collagen and Related Research, 1987
The in vitro self-assembly of type I and type III calf skin collagen in the presence of fibronectin was studied turbidimetrically. Fibronectin delayed the fibrillogenesis of type III collagen but accelerated that of type I collagen. The effect of fibronectin was concentration-dependent.
SPERANZA, MARIA LUISA   +2 more
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Topological Differences in the Expression of Collagen Type I and Collagen Type III mRNAs in the Rat Gingiva

Journal of Periodontology, 1994
Collagen mRNA levels in the gingival cells of molars and incisors in rats were measured and correlated with the ratio of interstitial collagen to DNA in these regions. Hybridization of 32P‐labeled specific cDNA probes for collagen types I and III with total RNA isolated from gingival tissue of rat molars and incisors showed that the steadystate levels ...
M, Redlich   +3 more
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Increased serum concentration of type IV collagen peptide and type III collagen peptide in hyperthyroidism

Clinica Chimica Acta, 1992
Serum concentration of type IV collagen peptide, the 7S domain of type IV collagen (type IV collagen 7S) and the amino terminal propeptide of type III procollagen (type III procollagen peptide) is thought to be a useful marker of progressive liver disease.
T, Inui   +4 more
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Collagen type III glomerulopathy

Kidney International, 2018
Helen P, Pizzo   +2 more
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Collagen types in fibrosarcoma: Absence of type III collagen in reticulin

Human Pathology, 1985
J, Hall   +4 more
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