Results 11 to 20 of about 140,913 (263)

Autoantibodies against basement membrane collagen type IV are associated with myocardial infarction [PDF]

International Journal of Cardiology: Heart & Vasculature, 2015
Background: Collagen type IV is the major constituent of basement membranes underlying endothelial cells and is important for endothelial cell attachment and function.
Olga McLeod, Pontus Dunér, Ann Samnegård, Per Tornvall, Jan Nilsson, Anders Hamsten, Eva Bengtsson   +6 more
doaj   +2 more sources

Collagen type IV at the fetal–maternal interface [PDF]

Placenta, 2015
Extracellular matrix proteins play a crucial role in influencing the invasion of trophoblast cells. However the role of collagens and collagen type IV (col-IV) in particular at the implantation site is not clear.Immunohistochemistry was used to determine the distribution of collagen types I, III, IV and VI in endometrium and decidua during the ...
Oefner, C.M., Sharkey, A., Gardner, L., Critchley, H., Oyen, M., Moffett, A.   +5 more
openaire   +4 more sources

Utilization of commercial collagens for preparing well-differentiated human beta cells for confocal microscopy

Frontiers in Endocrinology, 2023
IntroductionWith technical advances, confocal and super-resolution microscopy have become powerful tools to dissect cellular pathophysiology. Cell attachment to glass surfaces compatible with advanced imaging is critical prerequisite but remains a ...
Brianna R. Brennecke, Brianna R. Brennecke, Brianna R. Brennecke, USeong Yang, USeong Yang, USeong Yang, Siming Liu, Siming Liu, Fatma S. Ilerisoy, Fatma S. Ilerisoy, Fatma S. Ilerisoy, Beyza N. Ilerisoy, Beyza N. Ilerisoy, Beyza N. Ilerisoy, Aditya Joglekar, Aditya Joglekar, Lucy B. Kim, Lucy B. Kim, Spencer J. Peachee, Spencer J. Peachee, Syreine L. Richtsmeier, Syreine L. Richtsmeier, Samuel B. Stephens, Samuel B. Stephens, Edward A. Sander, Stefan Strack, Thomas O. Moninger, James A. Ankrum, James A. Ankrum, Yumi Imai, Yumi Imai, Yumi Imai   +31 more
doaj   +1 more source

Diagnostic performances of tumor necrosis factor-alpha and type IV collagen for diabetic nephropathy in type 2 diabetic patients [PDF]

Journal of Bioscience and Applied Research, 2022
Background: Diabetic nephropathy is a serious complication of both type 1 and type 2 diabetes. It's also called diabetic kidney disease (DKD). In the United States, about 1 in 3 people with diabetes have diabetic nephropathy.
Mohamed Omran, Anhar Elmetwaly, Tarek Emran, Ahmed Eldeeb, Arafa Belal, Faten Mohamed   +5 more
doaj   +1 more source

Cross-linking in type IV collagen [PDF]

Biochemical Journal, 1984
Type IV collagen could not be extracted from human placenta using 6M-urea containing 10mM-dithiothreitol, indicating that the type IV molecule is stabilized within the basement membrane by covalent cross-links. However, various forms of type IV collagen molecule were extractable by means of increasingly severe proteolytic conditions.
A J, Bailey, T J, Sims, N, Light
openaire   +2 more sources

Urinary excretion of type IV collagen as an early marker of renal fibrosis in patients with diabetes mellitus

Сахарный диабет, 2011
Aim. To determine the diagnostic value of urinary excretion of type IV collagen in patients with type 1 diabetes with different stages of nephropathy.Methods.
Irina Arkad'evna Bondar', Vadim Valer'evich Klimontov, Ekaterina Mikhailovna Parfent'eva, Vyacheslav Vital'evich Romanov, Alexander Petrovich Nadeev   +4 more
doaj   +1 more source

Porphyromonas gingivalis Induced Fragmentation of Type IV Collagen Through Macrophage-Activated MMP-9: (In Vitro Study of Collagenolytic Mechanism in Pathogenesis of Atherosclerotic Plaque Rupture)

Indonesian Biomedical Journal, 2009
BACKGROUND: Periodontitis is caused mostly by Porphyromonas gingivalis (P.gingivalis) and it is related to acute coronary syndrome. P.gingivalis  readily invades blood circulation and potentially induces collagenolytic activity of inflammatory cells that
Siti Nurul Mubarokah, I Dewa Agung Susilawati, Sumarno Sumarno, I Ketut Gedhe Muliartha, Djanggan Sargowo   +4 more
doaj   +1 more source

Pathomechanism of Renal Damage in Type 2 Diabetes Mellitus Patients

Indonesian Biomedical Journal, 2013
BACKGROUND: Hyperglycemia in diabetic patients cause both chronic inflammation and extracellular matrix accumulation that can lead to progressive renal damage.
Yuliana Sambara, Mansyur Arif, Uleng Bahrun   +2 more
doaj   +1 more source

Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen

International Journal of Biomaterials, 2012
The contact system of coagulation can be activated when in contact with biomaterials. As collagen is being tested in novel biomaterials in this study, we have investigated how type IV collagen affects plasma kallikrein and C1-inhibitor.
Sriram Ravindran, Marc Schapira, Philip A. Patston   +2 more
doaj   +1 more source

BIOCHEMICAL ASPECTS OF COLLAGEN TYPE IV METABOLISM IN PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE AND/OR OBSTRUCTIVE SLEEP APNEA/HYPOPNEA SYNDROME

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2019
Background. Gastroesophageal reflux disease (GERD) and obstructive sleep apnea/hypopnea syndrome (OSAHS) seem to be comorbid conditions. However, pathogenetic interactions between these conditions are not completely researched. Aim of the study.
Shaukovich Y., Shyshko V., Darashenka Y.
doaj   +1 more source