The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]
In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
Penning, R. +6 more
core +1 more source
Tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation [PDF]
The ability of tendons to glide smoothly during muscle contraction is impaired after injury by fibrous adhesions that form between the damaged tendon surface and surrounding tissues. To understand how adhesions form we incubated excised tendons in fibrin
Al-Youha Sarah +31 more
core +2 more sources
Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. [PDF]
Epicutaneous immunization is a potential non-invasive technique for antigen-specific immune-modulation. Topical application of protein antigens to barrier-disrupted skin induces potent antigen-specific immunity with a strong Th2-bias.
Strobel, S +9 more
core +2 more sources
The objective of this study was to develop a serum biochemical marker of the degradation of type III and IV collagens, as an index of synovium turnover, and evaluate its performance in patients with rheumatoid arthritis (RA).
Evelyne Gineyts +7 more
doaj +2 more sources
The clinical spectrum of type IV collagen mutations [PDF]
Clinical manifestations of type IV collagen mutations can vary from the severe, clinically and genetically heterogeneous renal disorder, Alport syndrome, to autosomal dominant familial benign hematuria. The predominant form of Alport syndrome is X-linked; more than 160 different mutations have yet been identified in the type IV collagen alpha 5 chain ...
Lemmink, H.H. +3 more
openaire +4 more sources
Topography and mechanical properties of single molecules of type I collagen using atomic force microscopy [PDF]
Although the mechanical behavior of tendon and bone has been studied for decades, there is still relatively little understanding of the molecular basis for their specific properties.
Bozec, L. +5 more
core +1 more source
Mucin 5AC (MUC5AC) hypersecretion induces airway narrowing in patients with asthma, which leads to breathing problems. We investigated the regulation of MUC5AC secretion by extracellular matrix (ECM) proteins in human primary airway epithelial cells from
Yuho Ito, Jun Iwashita, Jun Murata
doaj +1 more source
Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ +47 more
core +1 more source
Background. Obstructive sleep apnea/hypopnea syndrome (OSAHS) seems to have negative effect on the state of patients with gastroesophageal reflux disease (GERD).
Shalkovich Yu. Ya. +2 more
doaj +1 more source
Diagnostic significance of biochemical indicators of liver fibrogenesis in adolescents with obesity [PDF]
Non-alcoholic fatty liver disease occurs in most obese people, the main pathway of which is the process of fibrogenesis. The aim of this work was to determine the potential biomarkers for early diagnosis of liver fibrogenesis in adolescents with obesity.
O. V. Buznytska
doaj +1 more source

