Results 261 to 270 of about 21,718 (291)

Type VII Collagen Is Required for Ras-Driven Human Epidermal Tumorigenesis

Science, 2005
Type VII collagen defects cause recessive dystrophic epidermolysis bullosa (RDEB), a blistering skin disorder often accompanied by epidermal cancers. To study the role of collagen VII in these cancers, we examined Ras-driven tumorigenesis in RDEB keratinocytes. Cells devoid of collagen VII did not form tumors in mice, whereas those retaining a specific
Susana, Ortiz-Urda, John, Garcia, Cheryl L, Green, Lei, Chen, Qun, Lin, Dallas P, Veitch, Lynn Y, Sakai, Hyangkyu, Lee, M Peter, Marinkovich, Paul A, Khavari   +9 more
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Drug-induced epidermolysis bullosa acquisita with antibodies to type VII collagen

Journal of the American Academy of Dermatology, 2002
We describe a 73-year-old patient who had a subepidermal bullous eruption develop after a course of antibiotics, including vancomycin. The patient had deposits of IgA and IgG in the cutaneous basement membrane zone that were located on the dermal side of 1 M NaCl-treated autologous skin. By an enzyme-linked immunosorbent assay, the patient was found to
Delbaldo, Catherine Suzanne, Chen, Meilin, Friedli, André, Prins, Christa, Desmeules, Jules Alexandre, Saurat, Jean-Hilaire, Woodley, David T, Borradori, Luca   +7 more
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Epidermolysis bullosa acquisita: A disease of autoimmunity to type VII collagen

Journal of Autoimmunity, 1991
Epidermolysis bullosa acquisita (EBA) is one of a group of primary blistering diseases characterized by dermal/epidermal separation at the basement membrane (BM) of stratified squamous epithelium and IgG anti-BM autoantibodies (ABM). EBA ABMs can be distinguished from IgG ABMs in all other primary blistering diseases by their reactivity with the BM ...
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Type VII Collagen and 19-DEJ-1 Antigen

Archives of Dermatology, 1990
• The expression of type VII collagen and 19-DEJ-1 antigen was examined in 73 and 71 patients, respectively, with recessive dystrophic epidermolysis bullosa (RDEB), comprising gravis, mitis, inversa, and indeterminant subsets, to better determine the specificity and sensitivity of two monoclonal antibodies directed against these dermoepidermal ...
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Collagen type VII

1998
Shirley Ayad, Ray Boot-Handford, Martin J. Humphries, Karl E. Kadler, Adrian Shuttleworth   +4 more
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The Structure and Function of Type VII Collagen

Annals of the New York Academy of Sciences, 1990
R E, Burgeson, G P, Lunstrum, B, Rokosova, C S, Rimberg, L M, Rosenbaum, D R, Keene   +5 more
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Anchoring fibrils and type VII collagen in human breast.

Journal of submicroscopic cytology and pathology, 1990
A correlated ultrastructural and immunofluorescent study of anchoring fibrils and their principal constituent, type VII collagen, has been carried out on lobular epithelium from the normal adult human breast at different times in the menstrual cycle. Throughout the cycle, characteristic, cross-banded anchoring fibrils were seen inserting into the area ...
B P, Eyden, J, Ferguson
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Intraepidermal type VII collagen

Journal of the American Academy of Dermatology, 1990
Jo-David Fine, Yuji Horiguchi, David H. Stein, Nancy B. Esterly, Irene M. Leigh   +4 more
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The Structure of Type VII Collagena

Annals of the New York Academy of Sciences, 1985
R E, Burgeson, N P, Morris, L W, Murray, K G, Duncan, D R, Keene, L Y, Sakai   +5 more
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Type VII Collagen

2016
J.H. Mortensen, M.A. Karsdal
openaire   +1 more source