Results 91 to 100 of about 23,489 (224)

State-of-the-art diagnosis of autoimmune blistering diseases

Frontiers in Immunology
Autoimmune blistering disorders (AIBDs) are a heterogeneous group of approximately a dozen entities comprising pemphigus and pemphigoid disorders and dermatitis herpetiformis.
Nina van Beek, Maike M. Holtsche, Ingeborg Atefi, Henning Olbrich, Marie J. Schmitz, Jasper Pruessmann, Artem Vorobyev, Enno Schmidt, Enno Schmidt   +8 more
doaj   +1 more source

Factors impacting on left ventricular hypertrophy in haemodialysis patients [PDF]

, 2008
Left ventricular hypertrophy (LVH) and increases in large artery stiffness predict cardiovascular outcomes in patients with renal failure. What determines left ventricular mass index (LVMI) and large artery stiffness and the contribution toward LVH and
Chabu, James
core  

Tomato Juice Consumption Modifies the Urinary Peptide Profile in Sprague-Dawley Rats with Induced Hepatic Steatosis [PDF]

, 2017
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in Western countries, with a high prevalence, and has been shown to increase the risk of type 2 diabetes, cardiovascular disease (CVD), etc.
Albalat, Amaya, García-Alonso, Francisco Javier, González Barberá, Gonzalo, González-Barrio, Rocío, Martín-Pozuelo, Gala, Mischak, Harald, Mullen, William, Periago, María Jesús   +7 more
core   +1 more source

High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid

Frontiers in Medicine, 2018
Bullous pemphigoid (BP) presenting with erythema plaques and tense blisters is the most frequent autoimmune bullous disease. Immunologically, BP is characterized by the presence of circulating anti-epidermal basement membrane zone (BMZ) antibodies.
Hiroshi Koga, Kwesi Teye, Norito Ishii, Chika Ohata, Takekuni Nakama   +4 more
doaj   +1 more source

Identifying six single nucleotide variants in the COL17A1 gene that alter RNA splicing: database analysis and minigene assays

Scientific Reports
Collagen type XVII alpha 1 chain (COL17A1) is a protein in the collagen family crucial for maintaining the integrity of skin and epithelial tissues. It is also vital for enamel formation and plays a significant role in the differentiation of ameloblasts.
Yingfei Shao, Ran Zhang
doaj   +1 more source

Evaluation of Cacumen Platycladi Extract for Hair Loss Prevention: Mechanisms, Efficacy, and Clinical Application

Cosmetics
Hair loss is a prevalent condition with various causes, and effective treatments are in high demand. Cacumen Platycladi (Platycladus orientalis leaves), a traditional Chinese medicine, has been historically used to prevent hair loss.
Xue-Dong Bai, Yu-Chen Liu, Hong-Yun Zhao, Yi-Zhou Luo, Li-Jun Xu, Feng Luo   +5 more
doaj   +1 more source

Whole Exome Sequencing and Segregation Analysis Confirms That a Mutation in COL17A1 Is the Cause of Epithelial Recurrent Erosion Dystrophy in a Large Dominant Pedigree Previously Mapped to Chromosome 10q23-q24.

PLoS ONE, 2016
PurposeTo report identification of a COL17A1 mutation in a family with a corneal dystrophy previously mapped to chromosome 10q23-q24.MethodsWhole-exome sequencing was performed on DNA samples from five affected family members and two unrelated ...
Benjamin R Lin, Derek J Le, Yabin Chen, Qiwei Wang, D Doug Chung, Ricardo F Frausto, Christopher Croasdale, Richard W Yee, Fielding J Hejtmancik, Anthony J Aldave   +9 more
doaj   +1 more source

Cell-Penetrating Peptides, Electroporation, and Drug Delivery

, 2010
Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis.
Cahill, Kevin
core   +1 more source

Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoid.

PLoS ONE, 2014
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE autoantibodies and elevated eosinophil numbers. Although the pathogenicity of
Kelly N Messingham, Heather M Holahan, Alexandra S Frydman, Colleen Fullenkamp, Rupasree Srikantha, Janet A Fairley   +5 more
doaj   +1 more source

Human tenocytes are stimulated to proliferate by acetylcholine through an EGFR signalling pathway [PDF]

, 2012
Studies of human patellar and Achilles tendons have shown that primary tendon fibroblasts (tenocytes) not only have the capacity to produce acetylcholine (ACh) but also express muscarinic ACh receptors (mAChRs) through which ACh can exert its effects. In
Alexander Scott, Gloria Fong, Gustav Andersson, Ludvig J. Backman, Patrik Danielson   +4 more
core   +1 more source