Results 181 to 190 of about 23,489 (224)

Targeting collagen to optimize cancer immunotherapy. [PDF]

open access: yesExp Hematol Oncol
Wang Y   +9 more
europepmc   +1 more source

Severe tracheal involvement in type XVII collagen junctional epidermolysis bullosa

British Journal of Dermatology, 2023
In COLXVII-junctional epidermolysis bullosa, mucosal involvement remains inconsistent and is limited to the oral cavity and the oesophagus. We documented the observation of a patient presenting with tracheal damage.
Alizée Bozonnat   +7 more
openaire   +2 more sources

Abstract 1340: Type XVII collagen biology is central in the fibro-immune axis of tumor fibrosis: serological assessment of type XVII collagen

Cancer Research, 2023
Abstract Background: Collagens are the main components of the desmoplastic reaction of the tumors stroma, resulting in tumors fibrosis. Immuno-oncology (IO) is a central part of treating and understanding solid tumor patients. Alterations in the extracellular matrix (ECM) are known to contribute to tumor progression and metastasis ...
Marina Crespo-Bravo   +4 more
openaire   +1 more source

Two major 5′-untranslated regions for type XVII collagen mRNA

Journal of Dermatological Science, 2006
Type XVII collagen is an important structural component of keratinocyte hemidesmosomes and its functional loss in genetic or autoimmune disease results in blistering of the skin. In neoplastic tissue aberrant expression is seen dependent on the stage of the tumor.
van Zalen, Sebastiaan   +3 more
openaire   +2 more sources

Type XVII collagen and collagen-like molecules: related by more than a common motif

Seminars in Cell & Developmental Biology, 1996
Abstract Historically, collagens have been defined as extracellular matrix structural proteins whose sequence is characterized by many repeats of a three amino acid unit, GLY-X-Y. However, the latter motif has been identified in certain domains of a number of other proteins including the C1q subunit of complement, the collectins, the asymmetric form ...
Susan B. Hopkinson, Jonathan C.R. Jones
openaire   +1 more source

Targeting of the hNC16A collagen domain to dendritic cells induces tolerance to human type XVII collagen

Experimental Dermatology, 2012
Abstract:  Antibodies, specific to murine DEC205, can be used to target antigens to dendritic cells. The immunodominant domain of human type XVII collagen, hNC16A, was fused to this antibody (DEC‐hNC16A) and was administered as expression plasmid by gene gun transfection with the aim of inducing tolerance to human type XVII collagen in a skin ...
Monika, Ettinger   +9 more
openaire   +2 more sources

Two New Collagen Subgroups: Membrane-associated Collagens and Types XV and XVIII

1995
Publisher Summary This chapter discusses the two new subgroups among the large collagen gene family, the membrane-associated collagens, types XIII and XVII, and the subgroup formed, by collagen types XV and XVIII. Variant transcripts of collagens are discussed, as this phenomenon is pertinent for the members of both the new subgroups.
T, Pihlajaniemi, M, Rehn
openaire   +2 more sources

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