Results 31 to 40 of about 23,489 (224)

Bullous Dermolysis of the Newborn: Four New Cases and Clinical Review [PDF]

, 2013
Bullous dermolysis of the newborn ( BDN ) is a subtype of dystrophic epidermolysis bullosa caused by mutations in type VII collagen resulting in disorganized anchoring fibrils and sublamina densa blister formation.
Radkevich‐brown, Olga, Shwayder, Tor
core   +1 more source

Type XVII Collagen (BP180) and LAD-1 are Present as Separate Trimeric Complexes [PDF]

Journal of Investigative Dermatology, 1999
This study characterized the high molecular mass BP180 complex that is observed when unheated sodium dodecyl sulfate extracts of human skin or keratinocytes are subjected to sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting.
Pas, HH, Kloosterhuis, GJ, Nijenhuis, Albertine, de Jong, MCJM, van der Meer, JB, Jonkman, MF   +5 more
openaire   +3 more sources

Diagnosing Paraproteinemic Keratopathy: A Case Report

Case Reports in Ophthalmology, 2021
A 65-year-old man presented with bilateral, painless, progressive blurring of vision over 9 years. Slit-lamp examination revealed bilateral subepithelial corneal opacities in clusters located at the mid-periphery.
Eugenie Mok, Ka Wai Kam, Anthony J. Aldave, Alvin L. Young   +3 more
doaj   +1 more source

I.S.Mu.L.T. Achilles Tendon Ruptures Guidelines [PDF]

, 2018
This work provides easily accessible guidelines for the diagnosis, treatment and rehabilitation of Achilles tendon ruptures. These guidelines could be considered as recommendations for good clinical practice developed through a process of systematic ...
Alessio Giai Via,, Alfonso Maria Forte,, Angelo De Carli,, Anna, Collina, Antonio, Vadal\ue0, Asmaa, Mahmoud, Bernardi, Gabriele, Bernardo, Innocenti, Biagio, Moretti, Biz, Carlo, Calogero, Foti, Carlotta, Galeone, Clelia, Rugiero, Daniela, Buonocore, Domenico, Lupariello, Edoardo, Gaj, Eleonora, Piccirilli, Emanuela, Marsilio, Fantoni, Ilaria, Finotti, Paolo, Francesca, Veronesi, Francesco Di Pietto,, Frizziero, Antonio, Gamberini, Jacopo, Gasparini, Monica, Imma Di Lanno,, Johnny, Padulo, Leonardo, Pellicciari, Luca, Perazzo, Luigi Di Lorenzo,, Manuela, Verri, Marcello, Zappia, Maria Chiara Vulpiani,, Mario, Vetrano, Matteo, Baldassarri, Maurizia, Dossena, Michela, Bossa, Milena, Fini, Nicola, Maffulli, Oliva, Francesco, Pasquale, Farsetti, Pietro, Picerno, Roberto, Buda, Ruggieri, Pietro, Simone, Natali, Umberto, Tarantino, Vincenzo De Luna,, Vito, Chianca   +47 more
core   +1 more source

Fibroblast and keratinocyte gene expression following exposure to the extracts of holy basil plant (Ocimum tenuiflorum), malabar nut plant (Justicia adhatoda), and emblic myrobalan plant (Phyllanthus emblica)

Data in Brief, 2018
This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of holy basil plant (Ocimum tenuiflorum), sri lankan local name “maduruthala”, 0.1% and 0.01 ...
Takao Someya, Katsura Sano, Kotaro Hara, Yoshimasa Sagane, Toshihiro Watanabe, R.G.S. Wijesekara   +5 more
doaj   +1 more source

Case Report: A Rare Case of Pembrolizumab-Induced Bullous Pemphigoid

Frontiers in Immunology, 2021
The programmed cell death protein 1 inhibitor pembrolizumab, an immune checkpoint inhibitor, has subsequently been approved for the treatment of a wide variety of malignant tumors. Compared with conventional chemotherapy, immunotherapy is associated with
Xiaoyan Zhang, Dongjiang Sui, Dong Wang, Lina Zhang, Ruiyan Wang   +4 more
doaj   +1 more source

Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2

Frontiers in Immunology, 2018
Bullous pemphigoid (BP), the most frequent autoimmune bullous disorder, is a paradigmatic autoantibody-mediated disease associated with autoantibodies against BP180 (type XVII collagen, Col17).
Christian M. Karsten, Tina Beckmann, Maike M. Holtsche, Jenny Tillmann, Sabrina Tofern, Franziska S. Schulze, Eva Nina Heppe, Ralf J. Ludwig, Detlef Zillikens, Inke R. König, Jörg Köhl, Jörg Köhl, Enno Schmidt, Enno Schmidt   +13 more
doaj   +1 more source

Molecular architecture and function of the hemidesmosome [PDF]

, 2015
Hemidesmosomes are multiprotein complexes that facilitate the stable adhesion of basal epithelial cells to the underlying basement membrane. The mechanical stability of hemidesmosomes relies on multiple interactions of a few protein components that form ...
Gerhard Wiche, Gernot Walko, Maria J. Castañón   +2 more
core   +3 more sources

Recombinant Type XVII Collagen Inhibits EGFR/MAPK/AP-1 and Activates TGF-β/Smad Signaling to Enhance Collagen Secretion and Reduce Photoaging

Cosmetics
Studies have consistently shown that long-wave ultraviolet A (UVA) radiation triggers skin photoaging, which is evident as reduced elasticity, a loss of firmness, and signs of aging.
Ying He, Shiyu Yin, Ru Xu, Yan Zhao, Yuhang Du, Zhiguang Duan, Daidi Fan   +6 more
doaj   +1 more source

Autoimmunity against laminin 332

Frontiers in Immunology, 2023
Laminin 332 is a heterotrimeric structural protein of the basal membrane zone (BMZ) of the skin and adjacent mucosal tissues. The importance of laminin 332 for the structural integrity of the BMZ is demonstrated by mutations in any of the three genes ...
Sabrina Patzelt, Enno Schmidt, Enno Schmidt   +2 more
doaj   +1 more source