Results 121 to 130 of about 255,819 (284)

Magnetic Field Driven Microrobot Based on Hydrogels

Advanced Robotics Research, EarlyView.
Hydrogel‐based magnetic microrobots synergize remote magnetic control with the biocompatibility of flexible hydrogels, emerging as promising tools for minimally invasive biomedicine. This enables remotely controllable, untethered navigation within complex biological microenvironments.
Juncai Song, Yubing Guo
wiley   +1 more source

Mechanisms of Degradation of Collagen or Gelatin Materials (Hemostatic Sponges) in Oral Surgery: A Systematic Review

Surgeries
Objective: The goal of this systematic review was to identify the mechanisms associated with the enzymatic degradation of collagen and gelatin biomaterials and the possible associated flaws.
Maria Catarino, Filipe Castro, José Paulo Macedo, Otília Lopes, Jorge Pereira, Pedro Lopes, Gustavo Vicentis Oliveira Fernandes   +6 more
doaj   +1 more source

Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. [PDF]

, 2002
We show here the transient activation of the small GTPase Rac, followed by a rise in reactive oxygen species (ROS), as necessary early steps in a signal transduction cascade that lead to NFkappaB activation and collagenase-1 (CL-1)/matrix ...
Werb, Zena, Werner, Erica
core  

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Intralesional and topical treatments for Peyronie’s disease: a narrative review of current knowledge

Asian Journal of Andrology
Peyronie’s disease (PD) presents a multifaceted challenge in contemporary urological practice, marked by penile deformity, pain, and the potential for erectile dysfunction.
Antonio Minore, Loris Cacciatore, Fabrizio Presicce, Andrea Iannuzzi, Antonio Testa, Gianluigi Raso, Rocco Papalia, Marco Martini, Roberto Mario Scarpa, Francesco Esperto   +9 more
doaj   +1 more source

Bacterial Collagenase [PDF]

Journal of Bacteriology, 1945
openaire   +3 more sources

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Screening of a Plant Extract Library from the Greek Flora for Biological Activities Related to Anti-Aging Applications

Antioxidants
Characteristic manifestations of skin aging, due to either intrinsic or extrinsic factors, such as ultraviolet (UV) radiation and oxidative stress, include cell senescence, alterations in collagen and elastin networks, and melanogenesis disorders ...
Harris Pratsinis, Despoina D. Gianniou, Gabriela Belén Lemus Ringele, Adamantia Agalou, Asimina Fotopoulou, Xanthippi P. Louka, Christos Nastos, Eleftherios Kalpoutzakis, Aikaterini Argyropoulou, Dimitris Michailidis, Antonia Theodoridi, Ioanna Eleftheriadou, Adamantia Papadopoulou, Sentiljana Gumeni, Stavros Beteinakis, Konstantina Karamanou, Eleni Mavrogonatou, Georgios Stavropoulos, Dimitris Beis, Maria Halabalaki, Ioannis P. Trougakos, Dimitris Kletsas   +21 more
doaj   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source