Results 161 to 170 of about 300,263 (378)

Evaluation of collagenase gold plus BP protease in isolating islets from human pancreata [PDF]

open access: hybrid, 2018
Bashar Khiatah   +12 more
openalex   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang   +9 more
wiley   +1 more source

Screening of a Plant Extract Library from the Greek Flora for Biological Activities Related to Anti-Aging Applications

open access: yesAntioxidants
Characteristic manifestations of skin aging, due to either intrinsic or extrinsic factors, such as ultraviolet (UV) radiation and oxidative stress, include cell senescence, alterations in collagen and elastin networks, and melanogenesis disorders ...
Harris Pratsinis   +21 more
doaj   +1 more source

216 Jewish Hospital of St. Louis [PDF]

open access: yes, 1985
https://digitalcommons.wustl.edu/bjc_216/1175/thumbnail ...

core   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

open access: yesAdvanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai   +13 more
wiley   +1 more source

Anti-elastase and anti-collagenase potential of Lactobacilli exopolysaccharides on human fibroblast

open access: yesArtificial Cells Nanomedicine and Biotechnology, 2018
Mahdieh Shirzad   +3 more
semanticscholar   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma   +11 more
wiley   +1 more source

Cilostazol ameliorates collagenase-induced cerebral hemorrhage by protecting the blood–brain barrier

open access: yesJournal of Cerebral Blood Flow and Metabolism, 2017
Toshinori Takagi   +13 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy