Results 11 to 20 of about 300,263 (378)

Collagenase Nanoparticles Enhance the Penetration of Drugs Into Pancreatic Tumors.

ACS Nano, 2019
Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC) limits drug penetration into the tumor and is associated with poor prognosis.
Assaf Zinger, L. Koren, O. Adir, M. Poley, Mohammed Alyan, Zvi A Yaari, Nadav Noor, N. Krinsky, Assaf Simon, H. Gibori, Majd Krayem, Yelena Mumblat, Shira Kasten, Sivan Ofir, Eran Fridman, N. Milman, Michael M. Lübtow, Lior Liba, J. Shklover, Janna Shainsky‐Roitman, Y. Binenbaum, D. Hershkovitz, Z. Gil, Tal Dvir, R. Luxenhofer, R. Satchi‐Fainaro, Avi Schroeder   +26 more
semanticscholar   +3 more sources

Nature of the inhibitory effect of collagenase on phosphodiesterase activity.

Journal of Lipid Research, 1985
The level of phosphodiesterase (PDE) activity is lower in collagenase-isolated human fat cells than in adipose tissue fragments. The inhibition is not species-specific since collagenase also inhibits PDE in rat adipose tissue and bovine heart.
P Engfeldt, P Arner, J Ostman
doaj   +2 more sources

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts [PDF]

Journal of Experimental Medicine, 1985
Cachectin/TNF (tumor necrosis factor), an endotoxin-induced murine macrophage hormone implicated in the pathogenesis of cachexia and shock, has been found capable of stimulating collagenase and prostaglandin E2 (PGE2) production by isolated human ...
Jean-Michel Dayer, Bruce Beutler, Anthony Cerami   +2 more
semanticscholar   +2 more sources

Cosmetic and Dermatological Properties of Selected Ayurvedic Plant Extracts

Molecules, 2021
Due to the constantly growing interest in ingredients of natural origin, this study attempts to evaluate the possibility of using extracts from three Ayurvedic plants in preparations for the care and treatment of skin diseases.
Martyna Zagórska-Dziok, Aleksandra Ziemlewska, Tomasz Bujak, Zofia Nizioł-Łukaszewska, Zofia Hordyjewicz-Baran   +4 more
doaj   +1 more source

In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals

, 2020
Background Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous.
Chanipa Jiratchayamaethasakul, Yuling Ding, Ouibo Hwang, Seung-Tae Im, Yebin Jang, Seungwon Myung, J. Lee, Hyun-Soo Kim, Seok-Chun Ko, Seung-Hong Lee   +9 more
semanticscholar   +1 more source

Different collagenase delivery for Dupuytren disease in public hospitals

Australasian Journal of Plastic Surgery, 2020
**Background**: The delivery protocol of collagenase Clostridium histolyticum (collagenase) injection for Dupuytren’s disease is variable, due to limited evidence for any one approach and widespread ‘off-label’ delivery occurring in Australia.
Jessca A Paynter, Vicky Tobin, James CS Leong, Warren M Rozen, David J Hunter-Smith   +4 more
doaj   +1 more source

Pleiotropic functions of the tumor- and metastasis-suppressing Matrix Metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice [PDF]

, 2015
Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity which has onco-suppressive actions in numerous tumor ...
A Dufour, A Gutierrez-Fernandez, A Gutiérrez-Fernández, A Krüger, AM Tester, Ana Gutiérrez-Fernández, B Fingleton, B Fingleton, C López-Otín, C Soria-Valles, CM Overall, CT Guy, D Agarwal, Dylan R Edwards, E Dejonckheere, EI Deryugina, EM Bekes, EY Lin, EY Lin, G Christoffersson, G Dew, H Nozawa, J Decock, J Decock, J Decock, J Decock, J Schindelin, J Wyckoff, JE Maglione, JP Väyrynen, JP Witty, JT Korpi, JT Korpi, Julie Decock, K Almholt, L Sevenich, LH Palavalli, LJ McCawley, M Balbin, M Egeblad, M Hernández, M Lin, M Zhu, MM Gueders, N Fortelny, N Xu, P Li, P Lint Van, S Tazzyman, S Thirkettle, Sally Thirkettle, Stephen D Robinson, T Pellinen, T-Y Wu, V Knäuper, V Montel, W Wang, Wouter Hendrickx, Y Lang, Y-H Lin, Z Yang, Z-G Zhao, ZG Fridlender   +62 more
core   +3 more sources

Cyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
As the largest organ in human body, skin acts as a physicochemical barrier, offering protection against harmful environmental stressors, such as chemicals, pathogens, temperature and radiation.
Rita Favas, Janaína Morone, Rosário Martins, Vitor Vasconcelos, Graciliana Lopes   +4 more
doaj   +1 more source

Taxonomic and Enzymatic Characterization of Flocculibacter collagenilyticus gen. nov., sp. nov., a Novel Gammaproteobacterium With High Collagenase Production

Frontiers in Microbiology, 2021
Collagens from marine animals are an important component of marine organic nitrogen. Collagenase-producing bacteria and their collagenases play important roles in collagen degradation and organic nitrogen recycling in the ocean.
Jian Li, Jian Li, Jun-Hui Cheng, Zhao-Jie Teng, Zhong-Zhi Sun, Xiao-Yan He, Peng Wang, Peng Wang, Mei Shi, Xiao-Yan Song, Xiu-Lan Chen, Yu-Zhong Zhang, Yu-Zhong Zhang, Yu-Zhong Zhang, Xinmin Tian, Xi-Ying Zhang   +15 more
doaj   +1 more source

The effect of collagenase, water and calcium chloride on the removal of Salmo salar (salmon) and Oncorhynchus mykiss (trout) pin bones [PDF]

, 2018
The aim of this study was to determine the influence of the fillet structure on the deboning force required to remove salmon and trout pin bones. Salmon and trout fillets with differing fillet structure were used, in order to study the importance of the ...
Cassidy, Philip, Grigor, John M., Savage, Anne, Schroeder, Sarah, Stathopoulos, Constantinos E., Toepfl, Stefan, Wilkin, Jonathan D.   +6 more
core   +2 more sources