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Bacterial collagenases – A review
Critical Reviews in Microbiology, 2014 Bacterial collagenases are metalloproteinases involved in the degradation of the extracellular matrices of animal cells, due to their ability to digest native collagen. These enzymes are important virulence factors in a variety of pathogenic bacteria. Nonetheless, there is a lack of scientific consensus for a proper and well-defined classification of ...
Duarte, Ana Sofia +2 more
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Biochimie, 2005
Three mammalian collagenases (MMP-1, MMP-8, and MMP-13) belong to family of matrix metalloproteinases and are the principal secreted endopeptidases capable of cleaving collagenous extracellular matrix. In addition to fibrillar collagens, collagenases can cleave several other matrix and non-matrix proteins including growth factors, and this way regulate
Risto Ala-Aho, Veli-Matti Kahari
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Three mammalian collagenases (MMP-1, MMP-8, and MMP-13) belong to family of matrix metalloproteinases and are the principal secreted endopeptidases capable of cleaving collagenous extracellular matrix. In addition to fibrillar collagens, collagenases can cleave several other matrix and non-matrix proteins including growth factors, and this way regulate
Risto Ala-Aho, Veli-Matti Kahari
exaly +3 more sources
Nanoformulations based on collagenases loaded into halloysite/Veegum® clay minerals for potential pharmaceutical applications [PDF]
Colloids and Surfaces B: Biointerfaces, 2023 The design and development of nanomaterials capable of penetrate cancer cells is fundamental when anticancer therapy is involved. The use of collagenase (Col) is useful since this enzyme can degrade collagen, mainly present in the tumor extracellular ...
Marina Massaro +2 more
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Experimental Eye Research, 1969
A collagenase that can digest both collagen fibers in the stroma and the native collagen molecule was found in rabbit corneal epithelium, using a tissue culture assay. Calf, chicken and fetal calf serum added to the tissue culture media inhibited the collagenase, while human and rabbit serum were not inhibitory.
M, Itoi +4 more
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A collagenase that can digest both collagen fibers in the stroma and the native collagen molecule was found in rabbit corneal epithelium, using a tissue culture assay. Calf, chicken and fetal calf serum added to the tissue culture media inhibited the collagenase, while human and rabbit serum were not inhibitory.
M, Itoi +4 more
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Chick bone collagenase inhibitor and latency of collagenase
Biochemical and Biophysical Research Communications, 1981Abstract Collagenase and collagenase inhibitor were isolated from the culture fluid of embryonic chick bone. The inhibitor, separated as a high molecular weight aggregate (160,000–200,000 daltons) during gel filtration in 1M NaCl, dissociated in 6M urea to species of approx 25,000 daltons.
S, Sakamoto +4 more
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Neuropathology and Applied Neurobiology, 2006 We investigated the protein expression of gelatinases [matrix metalloproteinase (MMP)-2 and -9] and collagenases (MMP-8 and -13) in cerebrospinal fluid (CSF) from patients with bacterial (BM, n = 17) and aseptic (AM, n = 14) meningitis.
Timo Sorsa +2 more
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Collagenase and Collagenase Inhibitors in Bronchoalveolar Lavage Fluids
Chest, 1991Collagenase, collagenolytic activity and tissue inhibitor of metalloproteinases were evaluated in bronchoalveolar lavage from 25 patients with hypersensitivity pneumonitis and four control subjects. Patients were followed between two and three years, after which they were classified as "healed," "improved," or "worsened." In control samples ...
M, Selman +7 more
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Acta Pathologica Japonica, 1974
During metamorphosis, the collagen layer (basement lamella) of the resorbing tail fin of bullfrog tadpole was markedly disintegrated, and was invaded by mesenchymal cells from below, which contained cytoplasmic vacuoles enclosing collagen fibrils.
G, Usuku, M, Honya, I, Oyamada, T, Ogata
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During metamorphosis, the collagen layer (basement lamella) of the resorbing tail fin of bullfrog tadpole was markedly disintegrated, and was invaded by mesenchymal cells from below, which contained cytoplasmic vacuoles enclosing collagen fibrils.
G, Usuku, M, Honya, I, Oyamada, T, Ogata
openaire +2 more sources