Results 91 to 100 of about 3,127,959 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Everett Interpretation of Quantum Mechanics: Collected Works 1955-1980 with Commentary [Book Review] [PDF]

open access: yes, 2013
The so-called many-worlds interpretation of quantum mechanics is one of the main contenders in current approaches to solve the quantum-measurement problem.
Sauer, Tilman
core  

Theory and Practice of Data Citation

open access: yes, 2017
Citations are the cornerstone of knowledge propagation and the primary means of assessing the quality of research, as well as directing investments in science.
Silvello, Gianmaria
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Presentation of the New Collected Works by A. N. Tolstoy

open access: yesСлавянский мир в третьем тысячелетии
On October 17, 2024, a presentation of the first volume of the new collected works by A. N. Tolstoy took place at the A. N. Tolstoy’ Memorial Museum-Apartment on Spiridonovka.
Tatyana Ju. Kravchenko
doaj   +1 more source

Focus on cavity and circuit quantum electrodynamics in solids

open access: yesNew Journal of Physics, 2015
We introduce the works collected in the focus issue on Cavity and circuit quantum quantum electrodynamics in solids.
Yasuhiko Arakawa   +5 more
doaj   +1 more source

Live arts/arts alive : starcatchers research report 2011 [PDF]

open access: yes, 2011
Starcatchers is an innovative project which works in partnership with artists, arts venues child-care settings and families to experiment artistically with audiences of very young children, to encourage their participation and to develop exciting ...
Dunlop, Aline-Wendy   +4 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Re-reading of Pitirim Sorokin’s Sociology: To Commemorate The Publication of Thirteen Volumes of his Collected Works

open access: yesСоциологический журнал
This 30-volume edition of the Collected Works of Russian-American sociologist Pitirim Aleksandrovich Sorokin (1889–1968), the publication of which is ongoing with support from the Komi Republic Government (Russian Federation), is unique and the most ...
Nikolay A. Golovin
doaj   +1 more source

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