Results 81 to 90 of about 7,287,837 (290)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Focus on cavity and circuit quantum electrodynamics in solids

open access: yesNew Journal of Physics, 2015
We introduce the works collected in the focus issue on Cavity and circuit quantum quantum electrodynamics in solids.
Yasuhiko Arakawa   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Western Australia, Fremantle Harbour works longitudinal and cross sections of proposed works [cartographic material] /

open access: yes, 1901
"Copy of P.W.D. W.A. 8846".; "Progress plan revised to 31.12.1901".; "To accompany P.W.D., W.A. 8845.; Longitudinal and cross sections of Fremantle Harbour works.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map ...
Western Australia. Public Works Department.
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Collected Works of Florence Nightingale An Introduction to Her Life and Family

open access: yes
Florence Nightingale: An Introduction to Her Life and Family introduces the Collected Works by giving an overview of Nightingale's life and the faith that guided it and by outlining the main social reform concerns on which she worked from her "call to ...
Nightingale, Florence., McDonald, Lynn.
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

[The Phila. Gas Works., Engine Drawing Card, Sketch No. 8176]

open access: yes, 1931
This engine drawing card was created for the Philadelphia Gas Works, Class 4-32 C. Section N-4 C. Sketch 8176. Copy Spec.
Baldwin Locomotive Works
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy