Results 101 to 110 of about 3,127,959 (296)

A Report to the Committee on the Nobel Prize in Economic Science, 1985: The Contributions of James M. Buchanan to Economics and Political Economy [PDF]

open access: yes
Buchanan's contributions through 1984 are surveyed in six areas: (A) debt, fiscal illusion, and Keynesian criticisms, (B) London School of Economics cost approach, (C) methodological individualism and the economics of politics, (D) welfare price theory, (
Thomas Borcherding
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Applying Deep Machine Learning for psycho-demographic profiling of Internet users using O.C.E.A.N. model of personality

open access: yes, 2017
In the modern era, each Internet user leaves enormous amounts of auxiliary digital residuals (footprints) by using a variety of on-line services. All this data is already collected and stored for many years. In recent works, it was demonstrated that it's
Omelianenko, Iaroslav
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

WEMo (Wave Exposure Model): Formulation, Procedures and Validation [PDF]

open access: yes, 2007
This report describes the working of National Centers for Coastal Ocean Service (NCCOS) Wave Exposure Model (WEMo) capable of predicting the exposure of a site in estuarine and closed water to local wind generated waves. WEMo works in two different modes:
Fonseca, Mark S., Malhotra, Amit
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Review of: Gustav Bergmann, Collected Works [PDF]

open access: yes, 2006
Galavotti, M.C., Wachter, Daniel von
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Problems of old mining works in Protected Landscape Area Jeseníky [PDF]

open access: yesActa Montanistica Slovaca, 2008
The old mining works situated on the area of Landscape Protected Area of Jeseníky and responsible organizations is paidattention in this article. There are mentioned some data about the region Jeseníky and the separation into categories accordingto ...
Jitka Mučková
doaj  

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