Results 21 to 30 of about 1,532,862 (339)

Efficacy of combination therapy with pembrolizumab and axitinib for metastatic renal collecting duct cell carcinoma: A report on two cases

open access: yesIJU Case Reports, 2022
Introduction Immunotherapy‐based combinations have become the standard first‐line therapy for metastatic renal cell carcinoma. However, combined immunotherapy for renal collecting duct carcinoma had been reported, but its therapeutic efficacy had been ...
Shinji Tamada   +8 more
doaj   +1 more source

Patient Characteristics and Survival Outcomes of Non-Metastatic, Non-Clear Cell Renal Cell Carcinoma

open access: yesFrontiers in Oncology, 2022
BackgroundNon-clear cell renal cell carcinoma (ccRCC) includes histologically and molecularly distinct subtypes such as papillary, chromophobe, collecting duct, and sarcomatoid RCC, with an incidence ranging from 20% to 25%.
Josiah An   +6 more
doaj   +1 more source

A huge collecting duct carcinoma of the kidney in an elderly woman: Diagnosis and managment challenge (uncommon condition)

open access: yesUrology Case Reports, 2020
Collecting duct carcinoma, also known as Bellini duct carcinoma (BDC) is a rare type of renal tumor, arising from the distal collecting ducts. The prognosis of this disease is extremely poor due to its rapid progression with widespread metastasis.
Amine EL. Houmaidi   +5 more
doaj   +1 more source

A rare curative case of collecting duct carcinoma

open access: yesUrology Case Reports, 2022
Collecting duct carcinoma (CDC) is a rare form of renal carcinoma that has a poor prognosis. To date, there has been no report that the survival time of a patient with metastatic CDC could be more than six years.
Tielin Wu, Min Yin, Harris Haleem
doaj   +1 more source

Nivolumab and Ipilimumab Combination Immunotherapy for Patients with Metastatic Collecting Duct Carcinoma

open access: yesCase Reports in Urology, 2021
Collecting duct carcinoma (CDC) is a rare, extremely aggressive form of renal cancer. Recently, immune checkpoint inhibitors (ICI), anti-programmed death-1 (PD-1) antibody, and anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) antibody were ...
Tetsuya Danno   +5 more
doaj   +1 more source

Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]

open access: yes, 2012
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary   +2 more
core   +3 more sources

Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct [PDF]

open access: yes, 1997
We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct.
Andersen, D.   +8 more
core   +2 more sources

Ontogeny of purinergic receptor-regulated Ca2+ signaling in mouse cortical collecting duct epithelium [PDF]

open access: yes, 2002
Changes in ATP-induced increase in {[}Ca2+], during collecting duct ontogeny were studied in primary monolayer cultures of mouse ureteric bud (UB) and cortical collecting duct (CCD) cells by Fura-PE3 fluorescence ratio imaging.
Borscheid, R.   +4 more
core   +1 more source

Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]

open access: yes, 2017
Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
core   +1 more source

Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium

open access: yeseLife, 2018
Mutations in the polycystin genes, PKD1 or PKD2, results in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Although a genetic basis of ADPKD is established, we lack a clear understanding of polycystin proteins’ functions as ion channels.
Xiaowen Liu   +5 more
semanticscholar   +1 more source

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