Results 91 to 100 of about 1,775,938 (384)

Colonization and infection [PDF]

open access: yesCentral European Journal of Urology, 2014
Ureteral stenting (the insertion of the Double-J catheter) is and in the near future will remain one of the most common urological interventions. Consequently, bacterial and fungal complication of this stenting are in the focus of many controversial discussions [1].
openaire   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Squamous Cell Carcinoma Originating from a Crohn’s Enterocutaneous Fistula

open access: yesCase Reports in Surgery, 2017
Purpose. Squamous cell carcinoma (SCC) developing within fistulae and chronic wounds in patients with Crohn’s disease is a rare phenomenon with few reported studies in the literature.
Bogdan Protyniak   +2 more
doaj   +1 more source

Clinicopathologic characteristics of teenage sporadic colorectal cancer [PDF]

open access: yesKorean Journal of Clinical Oncology, 2017
Purpose Colorectal cancer (CRC) is generally considered a disease of old age. Most CRCs are diagnosed at age 50 and over. CRC rarely occurs in teenagers, and the clinical features and prognosis of CRC are not clear in this population.
Jae Jun Lee   +8 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

A priori mixed hadrons, hyperon non-leptonic decays, and the |\Delta I|=1/2 rule

open access: yes, 2001
The |\Delta I|=1/2 rule in non-leptonic decays of hyperons can be naturally understood by postulating a priori mixed physical hadrons, along with the isospin invariance of the responsible transition operator.
Garcia, A.   +2 more
core   +1 more source

Hyperbolic Components in Exponential Parameter Space [PDF]

open access: yes, 2004
We discuss the space of complex exponential maps $\Ek\colon z\mapsto e^{z}+\kappa$. We prove that every hyperbolic component $W$ has connected boundary, and there is a conformal isomorphism $\Phi_W\colon W\to\half^-$ which extends to a homeomorphism of ...
Baker   +6 more
core   +3 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Validation of a novel imaging-guided and anatomy-based classification system for anorectal fistulas: a retrospective clinical evaluation study [PDF]

open access: yesAnnals of Coloproctology
Purpose This study was conducted to evaluate the validity of a new imaging-guided, anatomy-based classification of anorectal fistulas in defining disease severity and predicting surgical outcomes.
Antonio Brillantino   +38 more
doaj   +1 more source

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