Results 111 to 120 of about 5,799,531 (403)
Left colon as a novel high-risk factor for postoperative recurrence of stage II colon cancer
Background It is not clear whether stage II colon and rectal cancer have the same risk factors for recurrence. Thus, the purpose of this study was to identify the risk factors for postoperative recurrence in stage II colorectal cancer.
Liming Wang +6 more
doaj +1 more source
Blue Star Healthy Colon Initiative [PDF]
IMPACT. 1: This collaborative effort has: Raised awareness about the burden of colon cancer. Provided education on prevention and early detection of colon cancer.
Fickle, Darla
core +1 more source
Heterogeneity in the Relationship between Disinfection By-Products in Drinking Water and Cancer: A Systematic Review. [PDF]
The epidemiological evidence demonstrating the effect of disinfection by-products (DBPs) from drinking water on colon and rectal cancers is well documented.
Benmarhnia, Tarik +4 more
core +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Elucidating Signal Transduction Modulatory Drug Target Network of Colon Cancer: A Network Biology Approach [PDF]
Latest evaluation and validation of cancer drugs and their targets has demonstrated the lack and inadequate development of new and better drugs, based on available protocols.
Biplab Bhattacharjee +5 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Objective To examine clinicopathologic characteristics and survival differences of colon cancer patients by different primary locations. Methods We retrospectively analyzed the medical records of 1088 colon cancer patients.
XU Hongli +5 more
doaj +1 more source
Background Accumulating evidence shows that Parkinson’s disease is negatively associated with colon cancer risk, indicating that Parkinson’s disease family proteins may be involved in the initiation of colon cancer. Here, we aimed to identify a Parkinson’
Qian Chen +12 more
doaj +1 more source
Computational modelling of the behaviour of biomarker particles of colorectal cancer in fecal matter [PDF]
Colorectal adenocarcinoma is one of the carcinogenic diseases that is increasing the morbidity and mortality rates worldwide. The disease initially occurs through the segregation of biomarker substances in the human system without manifesting symptoms ...
Hoyos, L., Suárez, G., Vallejo, E.
core
Mouse models of colorectal cancer. [PDF]
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip +2 more
core +2 more sources

