Results 131 to 140 of about 3,109,474 (268)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Efficacy of lateral lymph node dissection for local control of rectal cancer: A multicenter study

Annals of Gastroenterological Surgery
Background This study aimed to evaluate the efficacy of lateral lymph node dissection (LLND) for rectal cancer by comparing the local control in patients with and without pathological lateral lymph node metastasis (LLNM). Methods We included 189 patients
Yusuke Tanaka, Hitoshi Hino, Akio Shiomi, Kay Uehara, Jun Watanabe, Takeshi Nishikawa, Hideki Ueno, Yusuke Kinugasa, Kazushige Kawai, Yoichi Ajioka   +9 more
doaj   +1 more source

Colon Cancer [PDF]

Journal of the National Comprehensive Cancer Network, 2011
Al B, Benson, J Pablo, Arnoletti, Tanios, Bekaii-Saab, Emily, Chan, Yi-Jen, Chen, Michael A, Choti, Harry S, Cooper, Raza A, Dilawari, Paul F, Engstrom, Peter C, Enzinger, James W, Fleshman, Charles S, Fuchs, Jean L, Grem, James A, Knol, Lucille A, Leong, Edward, Lin, Kilian Salerno, May, Mary F, Mulcahy, Kate, Murphy, Eric, Rohren, David P, Ryan, Leonard, Saltz, Sunil, Sharma, David, Shibata, John M, Skibber, William, Small, Constantinos T, Sofocleous, Alan P, Venook, Christopher, Willett   +28 more
openaire   +2 more sources

Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9

, 2012
[[abstract]]PURPOSE: Prospero homeobox 1 (PROX1) has been shown to function as a tumor suppressor in various types of cancer. However, it promotes colon cancer progression.
Lu, MH;Huang, CC;Pan, MR;Chen, HH;Hung, WC
core   +1 more source

Programmable Pneumatic Actuator System for a Bioinspired Artificial Colon

Advanced Materials Technologies, EarlyView.
A modular soft robotic colon simulator driven by programmable pneumatic actuation is developed to mimic physiological and pathological‐like motility patterns of the large intestine. Finite element–guided design and distributed control enable anatomically realistic deformation for peristalsis, segmentation, and mass movements, supporting capsule ...
Andrew Bickerdike, Bo Tian, Xizheng Fang, Zepeng Wang, Yang Liu, Lucy Adams, Shyam Prasad   +6 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Monoclonal antibody for phosphorylated TRIO Y2681 that helps predict prognosis of post-operative colorectal cancer patients

BJC Reports
Background We previously reported that TRIO pY2681, a novel prognostic biomarker for CRC, can be detected by polyclonal antibodies (pAb). We have now developed a novel monoclonal antibody (mAb) that recognizes TRIO pY2681.
Taro Aoyama, Fumihiko Kakizaki, Hiroyuki Miyoshi, Masahiro Sonoshita, Hisatsugu Maekawa, Yoshiro Itatani, Kenji Kawada, Ryo Matsusue, Iwao Ikai, Koki Moriyoshi, Takaki Sakurai, Kazutaka Obama, Tosiya Shun Sato, Yoshiharu Sakai, Makoto Mark Taketo   +14 more
doaj   +1 more source

Cancer Of The Colon

Annals of Surgery, 1967
M, Galante, J E, Dunphy, W S, Fletcher
openaire   +3 more sources

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source