Results 91 to 100 of about 3,109,474 (268)

The current multidisciplinary management of rectal cancer

Annals of Gastroenterological Surgery
Multidisciplinary management of rectal cancer has rapidly evolved over the last several years. This review describes recent data surrounding total neoadjuvant therapy, organ preservation, and management of lateral pelvic lymph nodes. It then presents our
Neal Bhutiani, Oliver Peacock, Abhineet Uppal, Y. Nancy You, Brian K. Bednarski, John M. Skibber, Craig Messick, Michael G. White, George J. Chang, Tsuyoshi Konishi   +9 more
doaj   +1 more source

Co-occurrence and morphological analysis for colon tissue biopsy classification [PDF]

, 2006
Diagnosis and cure of colon cancer can be improved by efficiently classifying the colon tissue cells from biopsy slides into normal and malignant classes.
Rajpoot, Nasir M. (Nasir Mahmood), Qureshi, Hammad A., Rajpoot, Kashif, Masood, Khalid   +3 more
core  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Colonic Protein Fermentation and Promotion of Colon Carcinogenesis by Thermolyzed Casein [PDF]

, 1995
Thermolyzed casein is known to promote the growth of aberrant crypt foci (ACF) and colon cancer when it is fed to rats that have been initiated with azoxymethane.
Thompson, Lilian, Bruce, W. Robert, Archer, Michael C., Rémésy, Christian, Medline, Alan, Corpet, Denis E.   +5 more
core  

Comparison of Oncological Outcomes After Curative Resection for Right-side Colon Cancer and Left-side Colon Cancer: a Retrospective Observational Study [PDF]

Aim: This study aims to compare clinicopathological findings and oncological outcomes after curative resection between right-side colorectal carcinoma (RCC) and left-side colorectal carcinoma (LCC).
Mustafa Duman, Orhan Uzun, Mehmet Torun, Aziz Serkan Senger, Ömer Özduman, Mürşit Dinçer, Erdal Polat, Selçuk Gülmez, Ahmet Orhan Sunar   +8 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer

Annals of Gastroenterological Surgery
Aim To clarify the prognostic impact of positive lavage cytology diagnosed by immunostaining on long‐term outcomes following curative resection for pathological stage III colorectal cancer (CRC).
Akitoshi Nankaku, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Shoichi Manabe, Takuma Oishi, Kiyoshi Tone, Akifumi Notsu, Yusuke Kinugasa   +8 more
doaj   +1 more source

Transitional impact of short‐ and long‐term outcomes of a randomized controlled trial to evaluate laparoscopic versus open surgery for colorectal cancer from Japan Clinical Oncology Group Study JCOG0404

Annals of Gastroenterological Surgery, 2019
Background The JCOG0404 randomized controlled trial conducted to compare laparoscopic surgery (LAP) with open surgery (OP) for stage II/III colon cancer showed better short‐term outcomes and equal long‐term outcomes of LAP versus OP.
Shoichi Fujii, Tomonori Akagi, Masafumi Inomata, Hiroshi Katayama, Junki Mizusawa, Mitsuyoshi Ota, Shuji Saito, Yusuke Kinugasa, Shigeki Yamaguchi, Takeo Sato, Seigo Kitano, The Japan Clinical Oncology Group   +11 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source