Results 51 to 60 of about 1,403,065 (291)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Antipodean Intimacies: Medical Sex Advice for Women in the Australian colonies, 1857-1890 [PDF]

open access: yes, 2007
This article examines a genre of medical sex advice literature that emerged in colonial Australia at the close of the 19th century. While historians have examined medical discourse as a site for the production of raced bodies, this article points out ...
Samia Khatun
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Convicts and coolies : rethinking indentured labour in the nineteenth century [PDF]

open access: yes, 2009
This article seeks to shift the frame of analysis within which discussions of Indian indentured migration take place. It argues that colonial discourses and practices of indenture are best understood not with regard to the common historiographical ...
Allen Richard B.   +24 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

La historia como realidad y ficción: los distintos mundos de El hombre en el castillo

open access: yesNorteamérica, 2018
Se analiza la serie televisiva de El hombre en el castillo, una ucronía inspirada en la novela homónima de ciencia ficción de Philip K. Dick, donde se plantea una historia alternativa en la que Alemania y Japón han ganado la segunda guerra mundial a los
Nelson Arteaga Botello
doaj   +1 more source

Book Review: \u3cem\u3eThe Language of Disenchantment: Protestant Literalism and Colonial Discourse in British India\u3c/em\u3e [PDF]

open access: yes, 2013
A review of The Language of Disenchantment: Protestant Literalism and Colonial Discourse in British India by Robert A ...
Gonsalves, Roselle M.
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

En una tierra inmensa y sin clérigos. La fundación del seminario del Tucumán, 1587-1611

open access: yesSecuencia, 2016
En este trabajo se estudia la creación del seminario conciliar de la diócesis del Tucumán. Un colegio muy distinto a los ordenados en el concilio de Trento, tanto por sus características, como porque su fundación formal tuvo por objetivo que la Compañía ...
Leticia Pérez Puente
doaj   +1 more source

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