Results 101 to 110 of about 245,978 (301)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Biofilms and Benign Colonic Diseases. [PDF]

Int J Mol Sci, 2022
Songtanin B, Peterson CJ, Molehin AJ, Nugent K.   +3 more
europepmc   +1 more source

Multicenter, randomized study to optimize bowel for colon capsule endoscopy [PDF]

, 2017
AIM To assess the cleansing efficacy and safety of a new Colon capsule endoscopy (CCE) bowel preparation regimen. METHODS This was a multicenter, prospective, randomized, controlled study comparing two CCE regimens. Subjects were asymptomatic and average
Burch, Wilmot C., Jr, Kashyap, Pankaj K., Kastenberg, David, Papageorgiou, Neophytos, Pound, David C., Rex, Douglas K., Romeo, David P., Sainz, Ignacio Fernández-Urien, Sokach, Carly E.   +8 more
core   +2 more sources

Colonic Diverticular Disease

, 2021
Left-sided colonic diverticulitis represents one of the most common gastrointestinal conditions diagnosed in industrialized societies. Our understanding of the pathophysiology and management of this disease have changed over the past two decades. This chapter will review the epidemiology and pathophysiology of the disease. The current status of medical
Hall, Jason F., Bemelman, Willem A.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

[Computed tomography and magnetic resonance imaging of colonic diseases]. [PDF]

Radiologie (Heidelb), 2023
Scharitzer M, Lampichler K, Popp S, Mang T.   +3 more
europepmc   +1 more source

Experimental infection of newly weaned pigs with human and porcine strains of Serpulina pilosicoli [PDF]

, 1996
Cultures of Serpulina pilosicoli 95/1000, isolated from a pig with porcine intestinal spirochetosis (PIS), and S. pilosicoli WesB, isolated from an Aboriginal child with diarrhea, were used to infect 5-week-old newly weaned pigs. Four of 12 pigs infected
Trott, D.J., Huxtable, C.R., Hampson, D.J.   +2 more
core   +1 more source

Flavanol monomer-induced changes to the human faecal microflora [PDF]

, 2008
We have investigated the bacterial-dependent metabolism of ( − )-epicatechin and (+)-catechin using a pH-controlled, stirred, batch-culture fermentation system reflective of the distal region of the human large intestine.
Xenofon Tzounis, Jelena Vulevic, Gunter G. C. Kuhnle, Trevor George, Jadwiga Leonczak, Glenn R. Gibson, Catherine Kwik-Uribe, Jeremy P. E. Spencer, Wilson, Frayn, Gibson, Hughes, Garsetti, Matsui   +13 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source