Results 101 to 110 of about 178,735 (190)

Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: a stable isotope study [PDF]

, 2016
The short-chain fatty acids (SCFAs), acetate, propionate and butyrate, are bacterial metabolites that mediate the interaction between the diet, the microbiota and the host.
Annaert, Pieter, Boets, Eef, Courtin, Christophe M., De Preter, Vicky, De Vuyst, Luc, Delcour, Jan A., Deroover, Lise, Gomand, Sara V., Hamer, Henrike M., Preston, Tom, Van den Mooter, Guy, Verbeke, Kristin A., Vermeulen, Karen   +12 more
core   +1 more source

Using infrared gas sensors in an in-vitro dynamic gut model for detecting short-chain fatty-acids: Technical Report [PDF]

arXiv, 2019
Short-chain fatty acids (SCFAs), including acetate, propionate and butyrate, are organic fatty-acids that are produced when indigested carbohydrates are fermented in the colon by gut-bacteria. Butyrate is especially considered a beneficial compound in relation to gut health and the maintenance of colonic homeostasis.
arxiv  

The Effects Of 5-Ht4 Receptor Agonists On Interleukin-10 Knockout Mice [PDF]

, 2018
Recent studies have demonstrated that activation of the 5-HT4 receptors in the colonic mucosa can have healing and protective actions in experimental models of colitis.
Mylie, Quentin
core   +1 more source

Short-term exposure to high relative humidity increases blood urea and influences colonic urea-nitrogen metabolism by altering the gut microbiota

Journal of Advanced Research, 2022
Introduction: Colonic urea-nitrogen metabolites have been implicated in the pathogenesis of certain diseases which can be affected by environmental factors.
Hongmei Yin, Yadong Zhong, Hui Wang, Jielun Hu, Shengkun Xia, Yuandong Xiao, Shaoping Nie, Mingyong Xie   +7 more
doaj  

COULD THE INTESTINAL EPITHELIAL ALTERATIONS PROMOTED BY ROUX-EN-Y GASTRIC BYPASS EXPLAIN HIGHER TENDENCY FOR COLONIC DISEASES IN BARIATRIC PATIENTS? [PDF]

Arq Bras Cir Dig, 2021
Wendler E, Malafaia O, Ariede BL, Ribas-Filho JM, Czeczko NG, Nassif PAN.   +5 more
europepmc   +1 more source

Cutaneous Manifestations in Inflammatory Bowel Diseases [PDF]

, 2015
Inflammatory bowel diseases have a high frequency in Europe. They are chronic disorders that evolve with relapses and remissions. Clinical features include the signs of underlying inflammatory bowel disease and also signs of extraintestinal ...
Benea, Vasile, Costescu, Monica, Georgescu, Simona Roxana, Mitran, Cristina Iulia, Mitran, Madalina Irina, Sarbu, Maria Isabela, Tampa, Mircea   +6 more
core   +2 more sources

Advanced Targeted Drug Delivery for Colon Cancer Using Pristine and Surface-modified Hydroxyapatite Nanoparticles: Synthesis, Characterization, and pH-Responsive Release [PDF]

arXiv
Hydroxyapatite nanoparticles (HANs) have emerged as a promising candidate for targeted drug delivery in the treatment of colon cancer, a disease that remains one of the leading causes of cancer-related deaths globally. In this study, we synthesized and characterized HANs for their potential use as drug delivery vehicle for anticancer drugs specifically
arxiv  

Principal causal effect identification and surrogate endpoint evaluation by multiple trials [PDF]

arXiv, 2015
Principal stratification is a causal framework to analyze randomized experiments with a post-treatment variable between the treatment and endpoint variables. Because the principal strata defined by the potential outcomes of the post-treatment variable are not observable, we generally cannot identify the causal effects within principal strata. Motivated
arxiv  

Autologous cell transplantation for treatment of colorectal aganglionosis in mice

Nature Communications
Neurointestinal diseases cause significant morbidity and effective treatments are lacking. This study aimes to test the feasibility of transplanting autologous enteric neural stem cells (ENSCs) to rescue the enteric nervous system (ENS) in a model of ...
Weikang Pan, Ahmed A. Rahman, Takahiro Ohkura, Rhian Stavely, Kensuke Ohishi, Christopher Y. Han, Abigail Leavitt, Aki Kashiwagi, Alan J. Burns, Allan M. Goldstein, Ryo Hotta   +10 more
doaj   +1 more source

Oxidized Low-Density Lipoprotein Induces Reactive Oxygen Species-Dependent Proliferation of Intestinal Epithelial Cells

Pharmaceuticals
Background/Objectives: Oxidized low-density lipoprotein (ox-LDL) is a proinflammatory particle associated with various diseases and affects cell proliferation and viability in multiple cell types.
Eddy E. Gonzalez-Horta, Juan F. Burgueno, María J. Leiva, Carla Villavicencio, Fernando I. Kawaguchi, Hajar Hazime, Fátima Reyes, Viana Manrique-Suárez, Natalie C. Parra, Maria T. Abreu, Jorge R. Toledo   +10 more
doaj   +1 more source