Results 131 to 140 of about 9,867,423 (273)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Colonic Intussusception Caused by Colonic Lipoma

GE: Portuguese Journal of Gastroenterology, 2016
Filipa Ávila, José Renato Pereira, Maria Antónia Duarte   +2 more
doaj   +1 more source

Data from Vaccine against MUC1 Antigen Expressed in Inflammatory Bowel Disease and Cancer Lessens Colonic Inflammation and Prevents Progression to Colitis-Associated Colon Cancer

, 2023
Pamela Beatty, Sowmya Narayanan, Jean Gariépy, Sarangarajan Ranganathan, Olivera J. Finn   +4 more
openalex   +1 more source

Marked Response of Rat Ileal and Colonic Microbiota After the Establishment of Alzheimer’s Disease Model With Bilateral Intraventricular Injection of Aβ (1-42) [PDF]

, 2022
Qing Xu, Lingmiao Wen, Guihua Wei, Xiaoqin Zhao, Yanjun Liu, Wei Xiong, Tinglan Zhang, Yuqing Fan, Chunlan Chen, Chunxiao Xiang, Chang Chen, Yunhui Chen, Qiaozhi Yin, Tiane Zhang, Zhiyong Yan, Tian-e Zhang, Zhiyong Yan   +16 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Investigation of Colonic and Rectal Disease [Abridged] [PDF]

, 1972
R H Teague, A. E. Read
openalex   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

CLINICAL STUDY ON THE OPERATED COLONIC DIVERTICULAR DISEASE AND CASES OF COEXISTING CARCINOMA

, 1973
T. Kasukawa, Hiromichi FUCHINOUE
openalex   +1 more source

Multiparticulate Systems of Meloxicam for Colonic Administration in Cancer or Autoimmune Diseases [PDF]

, 2022
Eva Navarro-Ruíz, Covadonga Álvarez-Álvarez, María de los Ángeles Peña, Carlos Torrado‐Salmerón, Zaid Dahma, Paloma Marina de la Torre-Iglesias   +5 more
openalex   +1 more source