Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease [PDF]
, 1995 Li-Li Pan +3 more
openalex +1 more source
Powder Metallurgy Preparation of Metastable β Ti–Cr–Ge Alloys for Medical Applications
Advanced Engineering Materials, EarlyView.This study develops metastable β Ti–Cr–Ge alloys using powder metallurgy for biomedical implants. The Ti–10Cr–2Ge alloy exhibits superior mechanical performance with high yield strength (>1100 MPa), low Young's modulus (<85 GPa), and excellent strain hardening behavior.
Teddy Sjafrizal +3 more
wiley +1 more source
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Advanced Engineering Materials, EarlyView.Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez +2 more
wiley +1 more source
Feasibility of real-time strain elastography in colonic diseases. [PDF]
J Ultrasound, 2014 Giannetti A, Biscontri M, Matergi M.
europepmc +1 more source
Severe congenital neutropenia terminating in acute myeloid leukemia: Disease progression associated with mutations in the granulocyte-colony stimulating factor receptor gene [PDF]
, 1996 Ivo P. Touw, Fan Dong
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Advanced Functional Materials, EarlyView.Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na +15 more
wiley +1 more source
Colonic glycoproteins in monozygotic twins with inflammatory bowel disease
, 1991 Curt Tysk +5 more
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Colonic nitrite and immunoglobulin G concentrations in dogs with inflammatory bowel disease [PDF]
, 1997 Subhadra C. Gunawardana +3 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari +11 more
wiley +1 more source