Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction
Advanced Healthcare Materials, EarlyView.Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li +7 more
wiley +1 more source
Colon: a likely middleman connecting the liver, adipose tissue, and gut microbiota in MASLD. [PDF]
Am J Physiol Gastrointest Liver PhysiolPriyadarshini M, Layden BT.
europepmc +1 more source
Recombinant human granulocyte colony-stimulating factor therapy for patients with neutropenia and/or neutrophil dysfunction secondary to glycogen storage disease type 1b [PDF]
, 2001 Stanley Calderwood +6 more
openalex +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source
A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds
Advanced Healthcare Materials, EarlyView.Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico +8 more
wiley +1 more source
The expression of ferroptosis-related proteins GPX4 and PTGS2 in colonic tissues of pediatric Crohn's disease. [PDF]
J Pediatr (Rio J)Zhang S, Kang C, He X, Huang H, Xiao Q.
europepmc +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
Advanced Healthcare Materials, EarlyView.A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark +9 more
wiley +1 more source
Enhancing explainability of random survival forests in predicting stent patency risk for malignant colonic obstruction. [PDF]
BMC GastroenterolWan Y +6 more
europepmc +1 more source