Mathematical models for order of mutation problem in myeloproliferative neoplasm: non-additivity and non-commutativity [PDF]
In some patients of myeloproliferative neoplasm, two genetic mutations can be found: JAK2 V617F and TET2. When one mutation is present or not, the other mutation has different effects on regulating gene expressions. Besides, when both mutations are present, the order of occurrence might make a difference.
arxiv
Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm [PDF]
We develop a modeling framework for cancer progression that distinguishes the order of two possible mutations. Recent observations and information on myeloproliferative neoplasms are analyzed within our framework. In some patients with myeloproliferative neoplasms, two genetic mutations can be found, JAK2 V617F and TET2.
arxiv
Current Colorectal Cancer in Thailand [PDF]
This article aimed to summarize the current status of colorectal cancer (CRC) in Thailand. In brief, CRC is the third most common cancer and accounts for 11% of the cancer burden in Thailand.
Varut Lohsiriwat+3 more
doaj +1 more source
No more hide and seek:strategies to optimize diagnosis and endoscopic treatment of complex colorectal neoplasms [PDF]
Large non-pedunculated colorectal polyps and the occurrence of post-colonoscopy colorectal cancer are the subjects of the thesis “No more hide and seek”. The thesis shows that non-pedunculated colorectal cancers consist of a morphologically heterogeneous
Bogie, Roel Maria Michael
core +1 more source
Towards Understanding the Survival of Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms: An Investigation of Ensemble Feature Selection in the Prediction of Overall Survival [PDF]
Determining the most informative features for predicting the overall survival of patients diagnosed with high-grade gastroenteropancreatic neuroendocrine neoplasms is crucial to improve individual treatment plans for patients, as well as the biological understanding of the disease. Recently developed ensemble feature selectors like the Repeated Elastic
arxiv +1 more source
Epiplakin expression dynamics during colon carcinogenesis: Correlation with proliferation
Colorectal cancer poses a significant global health challenge, with a considerable proportion arising from colon adenomas. Understanding the molecules involved in the carcinogenesis process is crucial for improving colon cancer diagnosis and prognosis ...
Damla Gül Fındık+3 more
doaj +1 more source
Plasmacytoma as a Mimicker of Colonic Carcinoma in an Elderly Man
Multiple myeloma is a neoplastic proliferation of monoclonal plasma cells. Although it is usually restricted to the bone marrow, extraskeletal spread in the form of localised extramedullary collections of malignant plasma cells (plasmacytomas) can occur.
Sara Mathew George+3 more
doaj +1 more source
BlazeNeo: Blazing fast polyp segmentation and neoplasm detection [PDF]
In recent years, computer-aided automatic polyp segmentation and neoplasm detection have been an emerging topic in medical image analysis, providing valuable support to colonoscopy procedures. Attentions have been paid to improving the accuracy of polyp detection and segmentation.
arxiv
Colon Shape Estimation Method for Colonoscope Tracking using Recurrent Neural Networks [PDF]
We propose an estimation method using a recurrent neural network (RNN) of the colon's shape where deformation was occurred by a colonoscope insertion. Colonoscope tracking or a navigation system that navigates physician to polyp positions is needed to reduce such complications as colon perforation. Previous tracking methods caused large tracking errors
arxiv +1 more source
POLYMORPHISM OF THE COX-2 GENE AND SUSCEPTIBILITY TO COLON AND RECTAL CANCER
Background: The colorectal neoplasm is the fourth most common malignancy among males and the third among females. In the Western world is estimated that 5% of the population will develop it, making this disease a major public health problem.
Denise Camilios COSSIOLO+5 more
doaj +2 more sources