Results 71 to 80 of about 2,142,357 (377)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Investigating the Interactions Between Cyanobacteria and Vibrio parahaemolyticus [PDF]

open access: yes, 2014
One well-known pathogen that has been the topic of many recent studies is Vibrio parahaemolyticus, which causes thousands of foodborne illnesses a year, mostly from the ingestion of raw or undercooked oysters. It has been shown cyanobacteria can act as a
Ward, Caroline E
core   +1 more source

The counting of surface colonies of bacteria [PDF]

open access: yesEpidemiology and Infection, 1948
A colony count performed by spreading a known volume of suspension on the surface of a plate possesses certain advantages over other methods, of which the chief is ease of counting.The distribution of counts of several samples of the same suspension on medium of the same age and batch is as expected on statistical grounds.Different batches and ages of ...
openaire   +2 more sources

Colony Counts on Strips of Agar in Tubes [PDF]

open access: yesJournal of General Microbiology, 1950
SUMMARY: For viable counting, 0.1 ml. volumes of bacterial suspension were incorporated in 1.5-2 ml. nutrient agar, which after mixing was allowed to solidify in an almost horizontal test-tube so as to produce a 3–4 in. agar strip. After incubation in the vertical position, the counts of the strips gave estimates of a bacterial population which did not
A C, STIRLING, M K, STEVENS, D N, LAWLEY
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Combined stress from parasites, pesticides and lack of flowers drives bee declines [PDF]

open access: yes, 2015
Bees are subject to numerous pressures in the modern world. The abundance and diversity of flowers has declined, bees are chronically exposed to cocktails of agrochemicals, and they are simultaneously exposed to novel parasites accidentally spread by ...
Botias Talamantes, Cristina   +3 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial [PDF]

open access: yes, 2011
Background: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis.
A Nitkunan   +64 more
core   +3 more sources

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