Results 41 to 50 of about 6,208,881 (294)

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Effects of Neutralization and Crosslinking Agents on the Morphology of Chitosan Electrospun Scaffolds [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2017
Chitosan, a natural polymer derived from chitin by deacetylation process of chitin, has gained an enormous interest in tissue engineering due to its unique features such as antibacterial activity and wound healing properties. Electrospinning of acidified
Maryam Mashayekhi   +2 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A facile method to synthesis of a highly acrylated epoxidized soybean oil with low viscosity: Combined experimental and computational approach

open access: yesPolymer Testing, 2022
This investigation deals with the introduction of an efficient technique to acrylate almost all of the epoxide groups on epoxidized soybean oil (ESO) and synthesize a highly acrylated ESO (AESO) by using viscosity control agents (VCAs).
Sahar Abdollahi Baghban   +2 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Color Red [PDF]

open access: yes, 2017
A young veteran gets a call from Special Forces to come back to the Vietnam War. Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L.
Thompson, Dan
core   +1 more source

Color superfluidity of neutral ultra-cold fermions in the presence of color-flip and color-orbit fields

open access: yes, 2017
We describe how color superfluidity is modified in the presence of color-flip and color-orbit fields in the context of ultra-cold atoms, and discuss connections between this problem and that of color superconductivity in quantum chromodynamics.
de Melo, Carlos A. R. Sá   +1 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Effect of Pluronic Introduction to Polycaprolactone Substrate on the Blend Hydrophilicity by Molecular Dynamic Simulation [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2016
Poly()ε-caprolactone) ()PCL) has been widely investigated for medical applications because of its good physicochemical properties; however hydrophobic nature of PCL has been a colossal obstacle toward achieving scaffolds which offer satisfactory cell ...
Mohammad Masoud Mirhosseini   +2 more
doaj   +1 more source

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