Results 71 to 80 of about 5,872,931 (280)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Device to color modulate a stationary light beam gives high intensity [PDF]

, 1966
Signal controlled system color modulates a beam of light while also providing high intensity and a stationary beam, either collimated or focused. The color modulation acquired by the presented system can be compatible with any color film by employing ...
Gantz, W. A.
core   +1 more source

Hom-Lie color algebra structures

, 2010
This paper introduces the notion of Hom-Lie color algebra, which is a natural general- ization of Hom-Lie (super)algebras. Hom-Lie color algebras include also as special cases Lie (super) algebras and Lie color algebras.
Aizawa N., Albert A. A., Ammar F., Chaichian M., Chaichian M., Chaichian M., Goze M., Hartwig J. T., Lamei Yuan, Larsson D., Liu K., Makhlouf A., Myung H. C., Myung H. C., Scheunert M., Zhou J.   +15 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Valorization of American Barrel-Shoot Wastes: Effect of Post Fermentative Addition and Readdition on Phenolic Composition and Chromatic Quality of Syrah Red Wines

Molecules, 2020
The influence of post fermentative addition of American barrel-shoot wastes on phenolic composition and chromatic quality of Syrah red wines has been evaluated as an environmentally sustainable alternative to the conventional winemaking for avoiding the ...
Berta Baca-Bocanegra, Julio Nogales-Bueno, José Miguel Hernández-Hierro, Francisco José Heredia   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Color-Singlet and Color-Octet Contributions to $J/\psi$ Photoproduction

, 1996
I discuss the impact of color-octet contributions and higher-order QCD corrections on the cross section for inelastic $J/\psi$ photoproduction. The theoretical predictions are compared with recent experimental data obtained at HERA.Comment: LaTeX, 10 ...
Abe, Ahmed, Baier, Baier, Berger, Bodwin, Bodwin, Braaten, Braaten, Braaten, Brodsky, Cacciari, Cacciari, Cacciari, Cheung, Cho, Cho, Cho, Derrick, Derrick, Donnachie, Glück, Jung, Keung, Krämer, Krämer, Lai, Lepage, Ma, Martin, Michael Krämer, Roy, Saleev, Tang   +33 more
core   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

A Review on the Application of In Vitro and In Vivo Models of Cancerous Tumors for the Study of the Hyperthermia Effect

Basic & Clinical Cancer Research, 2019
Hyperthermia is a novel method for cancer therapy. To have the best control when heating tissues in  hyperthermia, the use of magnetic nanoparticles is suggested.
Zahra Zahedi-Tabar, Shadab Bagheri-Khoulenjani, Saeid Amanpour, Hamid Mirzadeh   +3 more
doaj   +1 more source