Results 91 to 100 of about 934,684 (307)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Difference and belonging, hopes and fears: parenting ‘mixed’ children and the implications for career development [PDF]

open access: yes, 2008
Rosalind Edwards, Professor in Social Policy and Director of the Families & Social Capital Research Group, at London South Bank University, discusses parenting issues and their implications for career development at the CeGS 10th Annual Lecture held at ...
Edwards, R., Edwards, Rosalind
core  

Toward an automatic color calibration for 3D displays

open access: yes, 2022
S.5-10This article considers the color correction of a 3D projection display installation. The system consists of a pair of projectors of the same model modified by INFITEC GmbH such that they can be used for projection of 3D contents.
Gerhardt, J., Thomas, J.-B.
core  

Evaluation of Color Performance of Video Cameras for Poultry House Monitoring Applications [PDF]

open access: yesBrazilian Journal of Poultry Science
This study examined the critical role of image color accuracy in surveillance systems, particularly in poultry houses, using affordable video cameras. Variations in commercial camera color processing can lead to inconsistent metrics.
CY Chou, TH Lin
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Color Edge Detection Hardware based on Geometric Algebra.

open access: yes, 2006
Modern techniques treat color images as separate monochrome images for processing. Partly, because there is no straightforward generalization of linear filters available for color.
B. Mishra   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Effect of Fabric Properties on Optical Parameters of Pigment-Based Inkjet Prints

open access: yesТехнологія і техніка друкарства
The article presents the results of an experimental study on the influence of the physical properties of natural fabrics on the optical characteristics of prints produced by direct inkjet printing with pigment inks. In response to the growing demand for
Катерина Олександрівна Чепурна   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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