Results 111 to 120 of about 934,684 (307)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Specifying color differences in a linear color space (LEF) [PDF]
This work presents a novel way of generating color differences for synthesizing artistically screened color images. A single color is specified by interacting with the mouse alternately on a constant luminance plane and on a constant hue plane within the
Ostromoukhov, V. +2 more
core
The Evaluation of Lightness and Chroma Difference for Images According to Color Difference Formulae
, 2011 The computation and evaluation of color difference for images is a hot topic. In order to explore the calculation method of evaluating color difference sensation for similar images, 68 pairs of test images were made, which were made from ISO SCID 400 ...
Yun Long Hao +4 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A color-difference formula for evaluating color pairs with no separation -- $\Delta E_{NS}$
, 2019 All color-difference formulas are developed to evaluate color differences for pairs of stimuli with hair-line separation. In printing applications, however, color differences are frequently judged between a pair of samples with no-separation because they
Fereshteh Mirjalili (17506938) +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
DEN OpenIntroduction The Kyoto Classification of Gastritis enables endoscopic assessment of Helicobacter pylori (H. pylori) infection status and gastric cancer risk.
Shotaro Oki +20 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Image Stitching Based on Color Difference and KAZE with a Fast Guided Filter. [PDF]
Sensors (Basel), 2023 Zhang C, Wang D, Sun H.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source