Results 51 to 60 of about 1,203,673 (294)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Self-similarities in the frequency-amplitude space of a loss-modulated CO$_2$ laser [PDF]

, 2005
We show the standard two-level continuous-time model of loss-modulated CO$_2$ lasers to display the same regular network of self-similar stability islands known so far to be typically present only in discrete-time models based on mappings.
Cristian Bonatto, E. Ott, J. A. C. Gallas, J. A. C. Gallas, Jason A. C. Gallas, Jean Claude Garreau, K. T. Alligood, R. Gilmore, R. C. Hilborn, S. H. Strogatz   +9 more
core   +3 more sources

Two-color discrete localized modes and resonant scattering in arrays of nonlinear quadratic optical waveguides

, 2005
We analyze the properties and stability of two-color discrete localized modes in arrays of channel waveguides where tunable quadratic nonlinearity is introduced as a nonlinear defect by periodic poling of a single waveguide in the array.
Kivshar, Y. S., Molina, M. I., Vicencio, R. A.   +2 more
core   +1 more source

Photo-stability of Coloring Constituents in Paprika Color

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1997
Capsanthin (CP) and esterified capsanthins are the main coloring constituents in paprika color. Several reports have suggested that esterified capsanthins are more stable to light than CP itself in paprika powder and paprika extract. To clarify whether this is so, the photo-stability of lauroylmyristoylcapsanthin (LM-CP) and CP was investigated in ...
Yukihiro GODA, Hiromichi NAKAMURA, Shiho SASAKI SAKAMOTO, Keiko ISHIKAWA, Tamio MAITANI, Takashi YAMADA   +5 more
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Can quantum chaos enhance stability of quantum computation? [PDF]

, 2001
We consider stability of a general quantum algorithm with respect to a fixed but unknown residual interaction between qubits, and show a surprising fact, namely that the average fidelity of quantum computation increases by decreasing average time ...
Benenti G, Chuang I L, Coppersmith D, Deutsch D, DiVincenzo D P, Feynman R P, Gea-Banacloche J, Gea-Banacloche J, Georgeot B, Georgeot B, Marko Znidaric, Nielsen M A, Peres A, Prosen T, Shor P W, Steane A, Steane A, Tian L, Tomaz Prosen   +18 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source