Results 221 to 230 of about 5,673,125 (350)

Signal Propagation in Protein Interaction Network during Colorectal Cancer Progression [PDF]

, 2013
Yang Jiang, Tao Huang, Lei Chen, Yufei Gao, Yu‐Dong Cai, Kuo‐Chen Chou   +5 more
openalex   +1 more source

Lessons from Hereditary Colorectal Cancer

Cell, 1996
K. Kinzler, B. Vogelstein
semanticscholar   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

Advanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao, Yu‐Bo Ma, Rui‐Hong Xia, Zheng‐Chen Jiang, Ying Zhou, Ya‐Nan Wang, Meng‐Yan Yang, Jing‐Jie Dai, Tao Zhu, Li‐Bin Pan, Li Yuan   +10 more
wiley   +1 more source

Evidence of fructose metabolism in colorectal cancer. [PDF]

Cell Death Discov
Sica GS, Bischof J, Funke L, Hartmut J, Candi E, Mauriello A, Scimeca M, Gao X, Savino L, Servadei F, Yang R, Wang L, Zhao Q, Chen WL, Sun Q, Jia W, Melino G.   +16 more
europepmc   +1 more source

A Paracrine-to-Autocrine Shunt of GREM1 Fuels Colorectal Cancer Metastasis via ACVR1C [PDF]

Huaixiang Zhou, Qunlong Jin, Fu Zhang, Yuan‐Han Yang, Yunfei Gao, Niu Wang, Bo Zhao, Long Gui, Li Jiang, Zijing Zhu, Ying Zhang, Yulong He, Ying Zhang, Shouqing Luo, Fu Li, Xudong Wu, Junjing Zhang, Xuetong Shen, Tao Wang, Youheng Jiang, Ningning Li   +20 more
openalex   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Correction: Prognostic and predictive molecular biomarkers in colorectal cancer. [PDF]

Front Oncol
Zhang J, Zhu H, Liu W, Miao J, Mao Y, Li Q.   +5 more
europepmc   +1 more source

Cardiovascular toxicity of Fruquintinib in patients with colorectal and other cancers: a systematic review and meta-analysis [PDF]

A. Nouri, Ameer Awashra, Dawoud Hamdan, Islam Rajab, Abdalhakim Shubietah, Yahya Ismail, Anan Abu Rmilah   +6 more
openalex   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Immunotherapy for precision medicine in colorectal cancer. [PDF]

Expert Rev Precis Med Drug Dev
Cao M, Xu M, Bairmani Z, Bashir B, Waldman SA, Snook AE.   +5 more
europepmc   +1 more source