Results 271 to 280 of about 141,334 (303)

Hepatectomy for liver metastasis of colorectal cancer

International Journal of Colorectal Disease, 2008
The objective of this study was to investigate whether hepatic resection (HR) can increase the survival of liver metastasis of colorectal cancer (CRC).CRC patients (n=669) with liver metastasis treated at the Zhongshan Hospital, Fudan University from 1/2000 to 7/2007 were included in the study to investigate the relationship between HR and cancer ...
Jianmin, Xu, Ye, Wei, Yunshi, Zhong, Jia, Fan, Jian, Zhou, Lunxiu, Qin, Li, Ren, Xinyu, Qin   +7 more
openaire   +2 more sources

Absence of colorectal cancer metastasis to the cirrhotic liver

The American Journal of Surgery, 1992
Hepatic metastasis of colorectal cancer was found in 40 (16%) of 250 patients with colorectal cancer treated in our department during the past 5 years. Liver cirrhosis was not found among the 40 patients with metastases (16%) but was present in 46 (21.9%) of the 210 nonmetastatic patients, with a significant difference between the two groups (p less ...
S, Uetsuji, M, Yamamura, K, Yamamichi, Y, Okuda, H, Takada, K, Hioki   +5 more
openaire   +2 more sources

Histopathologic characteristics of colorectal cancer with liver metastasis

Diseases of the Colon & Rectum, 1999
Although prognostic factors of colorectal cancer have been studied, factors associated with liver metastasis have not been fully investigated. The aim of this study was to clarify the histopathologic characteristics of colorectal cancer with liver metastasis.We performed a retrospective histopathologic study on 335 patients who underwent resection of ...
Y, Adachi, M, Inomata, K, Kakisako, K, Sato, N, Shiraishi, S, Kitano   +5 more
openaire   +2 more sources

Stereotactic ablative radiotherapy for colorectal cancer liver metastasis

Seminars in Cancer Biology, 2021
Survival improvement of colorectal liver metastasis (CRLM) benefits from systemic therapy and metastasis-directed local therapy. Stereotactic ablative body radiotherapy (SABR), as a new efficient metastasis-directed local therapy with a systematic impact, plays a vital role in CRLM multidisciplinary treatment.
Hao Wang, Xuemin Li, Ran Peng, Yuxia Wang, Junjie Wang   +4 more
openaire   +2 more sources

Immunomodulatory molecules in colorectal cancer liver metastasis

Cancer Letters
Colorectal cancer (CRC) ranks as the third most common cancer and the second leading cause of cancer-related deaths. According to clinical diagnosis and treatment, liver metastasis occurs in approximately 50 % of CRC patients, indicating a poor prognosis. The unique immune tolerance of the liver fosters an immunosuppressive tumor microenvironment (TME).
Wei-Shuai Kong, Jia-Jun Li, Yu-Qing Deng, Huai-Qiang Ju, Rui-Hua Xu   +4 more
openaire   +2 more sources

Development of a Reliable Colorectal Cancer Liver Metastasis Model

Journal of Surgical Research, 1996
The liver is the most frequent and most fatal site of distant spread of colorectal cancer. Most current animal models of liver metastases utilize direct liver or intravascular injection (dissimilar to mechanisms of metastasis) or immunosuppression to establish metastases.The aim of this study was to develop a reliable rat model of liver metastases in ...
M I, Brand, S, Casillas, D W, Dietz, J W, Milsom, A, Vladisavljevic   +4 more
openaire   +2 more sources

Nanog: A Potential Biomarker for Liver Metastasis of Colorectal Cancer

Digestive Diseases and Sciences, 2012
At present, the relationship between Nanog expression and the biological behavior and prognosis of colorectal cancer is still unclear.The purpose of this study was to evaluate the expression and regulatory effects of Nanog in colorectal cancer and the correlation between Nanog protein expression and the prognosis of patients with colorectal cancer.The ...
Feng, Xu, Chaoliu, Dai, Rui, Zhang, Yang, Zhao, Songlin, Peng, Changjun, Jia   +5 more
openaire   +2 more sources

Cryosurgery in the treatment of liver metastasis from colorectal cancer

Journal of Gastrointestinal Surgery, 1997
Cryotherapy is a treatment modality that can offer reasonable hope to patients with unresectable metastatic colorectal cancer to the liver and those with poor hepatic reserve or comorbid conditions that preclude major resection. It can be used for more than one liver lesion, for bilobar disease, and as an aid in segmental resections.
T S, Ravikumar, R, Sotomayor, R, Goel
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Synchronous liver metastasis in colorectal cancer in Sri Lanka

Indian Journal of Gastroenterology, 2010
To assess the incidence of synchronous colorectal liver metastasis in patients referred to a tertiary referral center in Sri Lanka and to evaluate the differences in the clinicopathological features of patients with and without synchronous metastasis.Records of 438 patients were retrospectively analyzed.
Rohan Chaminda, Siriwardana, S Ruwan E, Wijesuriya, Sumudu K, Kumarage, Kemal I, Deen   +3 more
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Biology of Colorectal Cancer Liver Metastasis

1998
Metastasis—the spread of malignant tumor cells from a primary neoplasm to distant parts of the body where they multiply to form new growths—is a major cause of death from cancer. The treatment of metastatic cancer poses a major problem to clinical oncologists because the presence of multiple metastases makes complete eradication by surgery, irradiation,
Chul Ho Cho, Robert Radinsky
openaire   +1 more source