Results 261 to 270 of about 4,253,992 (294)

Development of a Reliable Colorectal Cancer Liver Metastasis Model

Journal of Surgical Research, 1996
The liver is the most frequent and most fatal site of distant spread of colorectal cancer. Most current animal models of liver metastases utilize direct liver or intravascular injection (dissimilar to mechanisms of metastasis) or immunosuppression to establish metastases.The aim of this study was to develop a reliable rat model of liver metastases in ...
M I, Brand, S, Casillas, D W, Dietz, J W, Milsom, A, Vladisavljevic   +4 more
openaire   +2 more sources

Biology of Colorectal Cancer Liver Metastasis

1998
Metastasis—the spread of malignant tumor cells from a primary neoplasm to distant parts of the body where they multiply to form new growths—is a major cause of death from cancer. The treatment of metastatic cancer poses a major problem to clinical oncologists because the presence of multiple metastases makes complete eradication by surgery, irradiation,
Chul Ho Cho, Robert Radinsky
openaire   +1 more source

Synchronous liver metastasis in colorectal cancer in Sri Lanka

Indian Journal of Gastroenterology, 2010
To assess the incidence of synchronous colorectal liver metastasis in patients referred to a tertiary referral center in Sri Lanka and to evaluate the differences in the clinicopathological features of patients with and without synchronous metastasis.Records of 438 patients were retrospectively analyzed.
Rohan Chaminda, Siriwardana, S Ruwan E, Wijesuriya, Sumudu K, Kumarage, Kemal I, Deen   +3 more
openaire   +2 more sources

Serum CD10 is associated with liver metastasis in colorectal cancer

Journal of Surgical Research, 2014
Colorectal cancer (CRC) is the third leading cause of cancer death in Japan. CD10 expression is closely associated with liver metastasis. In the present study, we explored the possibility of serum CD10 as a marker of liver metastasis in CRC.BALB/c mouse with subcutaneous tumor of syngeneic CT26 CRC cells were examined serum CD10. In 84 CRC patients and
Takamitsu Sasaki, Hiroki Kuniyasu, Yi Luo, Rina Fujiwara, Misaho Kitayoshi, Eriko Tanabe, Daisuke Kato, Satoshi Shinya, Kiyomu Fujii, Hitoshi Ohmori, Yuichi Yamashita   +10 more
openaire   +2 more sources

Living Donor Liver Transplantation for Colorectal Cancer Liver Metastasis

Gastroenterology Clinics of North America
Liver transplantation (LT) for unresectable colorectal liver metastases has evolved from early feasibility studies to a biologically selected, multidisciplinary strategy for patients with liver-confined disease. Evidence from the SECA program and randomized data from TransMet support meaningful survival in carefully chosen candidates.
Mario, Spaggiari, Elif, Kortan, Maria Jimena, Alaniz   +2 more
openaire   +2 more sources

Nanog: A Potential Biomarker for Liver Metastasis of Colorectal Cancer

Digestive Diseases and Sciences, 2012
At present, the relationship between Nanog expression and the biological behavior and prognosis of colorectal cancer is still unclear.The purpose of this study was to evaluate the expression and regulatory effects of Nanog in colorectal cancer and the correlation between Nanog protein expression and the prognosis of patients with colorectal cancer.The ...
Feng, Xu, Chaoliu, Dai, Rui, Zhang, Yang, Zhao, Songlin, Peng, Changjun, Jia   +5 more
openaire   +2 more sources

Cryosurgery in the treatment of liver metastasis from colorectal cancer

Journal of Gastrointestinal Surgery, 1997
Cryotherapy is a treatment modality that can offer reasonable hope to patients with unresectable metastatic colorectal cancer to the liver and those with poor hepatic reserve or comorbid conditions that preclude major resection. It can be used for more than one liver lesion, for bilobar disease, and as an aid in segmental resections.
T S, Ravikumar, R, Sotomayor, R, Goel
openaire   +2 more sources

A prognostic indicator for the resection of liver metastasis of colorectal cancer

Surgery Today, 2013
We investigated the predictive indicator for a good prognosis of surgical resection for liver metastasis of colorectal cancer.Between 1990 and 2009 at our institute, 117 patients underwent 132 hepatic resections for liver metastasis of colorectal cancer. The clinical, pathological, and outcome parameters affecting their prognoses were analyzed.
Ryosuke, Amano, Nobuya, Yamada, Bunzo, Nakata, Kenjiro, Kimura, Masakazu, Yashiro, Masaichi, Ohira, Kosei, Hirakawa   +6 more
openaire   +2 more sources

[Chemotherapy for liver metastasis of colorectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy, 2005
In colorectal cancer, liver metastasis is the most common and most important prognostic factor. Although surgical resection is the first choice of treatment for liver metastasis of colorectal cancer, there are many cases we cannot choose the surgical treatment. The chemotherapy is very important in such cases. We examined 18 cases of unresectable liver
Masahiro, Amano, Takahiro, Niinobu, Yutaka, Itani, Yasuaki, Nishikawa, Sumiko, Nakagawa, Naozumi, Higaki, Hirohito, Hayashida, Makoto, Fujita, Masato, Sakon   +8 more
openaire   +1 more source

Colorectal Cancer Statistics, 2023

Ca-A Cancer Journal for Clinicians, 2023
Rebecca L. Siegel, Ahmedin Jemal, Andrea Cercek   +2 more
exaly