Results 241 to 250 of about 4,253,992 (294)

Inosine alleviates colorectal cancer liver metastasis by promoting M1 macrophage polarization and modulating the PI3K/AKT signaling pathway. [PDF]

Front Immunol
Dong Y, Ma Y, Yu Q, Shi Z, Wang C, Che Y, Liu H, Wan D, Shao W, Xiao H.   +9 more
europepmc   +1 more source

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

Interdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh, Manjeet Kumar, Kajal Kamra   +2 more
wiley   +1 more source

Metabolic syndrome in colorectal cancer liver metastasis: metabolic reprogramming and microenvironment crosstalk. [PDF]

Front Immunol
Ma Z, Wang S, Liu S, Yang W, Hu J, Lv L, Yu Q, Lu Y.   +7 more
europepmc   +1 more source

Characteristics of ascitic fluid and diagnosis of bacterial peritonitis in malignant ascites: An observational study

Journal of Hospital Medicine, EarlyView.
Abstract Background Bacterial peritonitis in patients with malignant ascites (BP‐MA) is an understudied, high‐mortality condition. While ascitic polymorphonuclear (PMN) cell count ≥ 250 cells/mm3 defines the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis, an ascitic fluid parameter for the diagnosis of BP‐MA has not ...
Mark M. Kelly, Nicole Johnston, Joanne Kuznicki, Stacy A. Johnson, Hannah Imlay   +4 more
wiley   +1 more source

Neutrophil extracellular traps regulate LDHA expression to promote colorectal cancer liver metastasis. [PDF]

J Transl Med
Li N, Yang S, Hu C, Zheng J, Yang H, Jiang T, Li X, Han Q, Zhang X, Yang Y, Khan S, Sun B.   +11 more
europepmc   +1 more source

Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Ascelia‐Manganese‐Based MRI Contrast Agent (ACE‐MBCA) in Adult Subjects With and Without Hepatic Impairment

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Orally administered Ascelia‐manganese‐based contrast agent (ACE‐MBCA) is used for liver MRI, but its feasibility in patients with hepatic dysfunction remains unknown. Purpose To investigate the pharmacokinetics (PK), pharmacodynamics, and safety of ACE‐MBCA in subjects without/with hepatic impairment.
Amit G. Singal, Eric Lawitz, Andreas Norlin, Nadilka Hettiarachchige, Thomas Bengtsson, Bachir Taouli   +5 more
wiley   +1 more source

OTUD6B-mediated K48 deubiquitination of FXR1 forms a positive feedback loop activating MEK2/ERK signaling in colorectal cancer liver metastasis. [PDF]

Cell Death Dis
Lu Y, Liu J, Li YN, Xiang L, Song GB, Peng T, Wang Z, Yang X, Ying HQ, Cheng XX.   +9 more
europepmc   +1 more source

SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts. [PDF]

Cancer Res
Liu S, Zhang Z, Wang Z, Liu C, Liang G, Xu T, Li Z, Duan X, Xu G, Feng X, Feng Q, Wang Q, Han D, Zhang C, Li J, Shen L.   +15 more
europepmc   +1 more source

Single-cell transcriptomic profiling reveals liver fibrosis in colorectal cancer liver metastasis. [PDF]

Exp Mol Med
Deng Y, Guo C, Liu X, Li X, Liu J, Liu W, Chen J, Huang Z, Zhang Y, Bi X, Zhao J, Zhou J, Li Z, Wu H, Xing B, Chen Q, Zhao H.   +16 more
europepmc   +1 more source

Ex vivo modelling of human colorectal cancer liver metastasis by normothermic machine perfusion. [PDF]

Mol Cancer
Trebo M, Maurer T, Krendl FJ, Salcher S, Martowicz A, Hautz T, Sopper S, Amann A, Cardini B, Poelsler LH, Mair A, Hofmann J, Meszaros AT, Hermann M, Günther M, Ormanns S, Trajanoski Z, Schneeberger S, Wolf D, Oberhuber R, Pircher A.   +20 more
europepmc   +1 more source