Results 131 to 140 of about 789,387 (385)

A prospective multiple case study of the impact of emerging scientific evidence on established colorectal cancer screening programs: a study protocol. [PDF]

open access: yes, 2012
BackgroundHealth-policy decision making is a complex and dynamic process, for which strong evidentiary support is required. This includes scientifically produced research, as well as information that relates to the context in which the decision takes ...
Dobrow, Mark J   +3 more
core   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Systematic review of colorectal cancer screening guidelines for average-risk adults: Summarizing the current global recommendations

open access: yesWorld Journal of Gastroenterology, 2018
AIM To summarize and compare worldwide colorectal cancer (CRC) screening recommendations in order to identify similarities and disparities. METHODS A systematic literature search was performed using MEDLINE, EMBASE, Scopus, CENTRAL and ISI Web of ...
Florence Benard   +3 more
semanticscholar   +1 more source

Factors Influencing Colorectal Cancer Screening Among Thais in the U.S. [PDF]

open access: yes, 2019
This study examined factors related to colorectal cancer (CRC) screening uptake among Thais in the United States. A total of 121 Thais between 50 and 75 years of age, who were married and living in southern California participated in the survey (mean age 
Lee, Eunice   +4 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Colorectal cancer in Malaysia: Its burden and implications for a multiethnic country

open access: yesAsian Journal of Surgery, 2017
Background: This study aims to provide an analytical overview of the changing burden of colorectal cancer and highlight the implementable control measures that can help reduce the future burden of colorectal cancer in Malaysia.
Sajesh K. Veettil   +4 more
doaj   +1 more source

Colorectal Cancer Screening Quality Improvement: A FITKit Mailing Initiative [PDF]

open access: yes, 2019
According to the American Cancer Society, colorectal cancers are diagnosed in 1 in 22 men and 1 in 24 women in their lifetime. Despite the wide range of effective CRC screening options available in the US, the Hudson Headwaters Health Network (HHHN) has ...
Kratzer, Isabella
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The Role of Microbiota and Early Detection in Colorectal Cancer Through Fecal Screening

open access: yesMajalah Kedokteran Andalas
Objective: This literature review explores the link between gut microbiota and colorectal cancer, emphasizing early detection through fecal screening.
Muhammad Iqbal
doaj   +1 more source

Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline

open access: yesBritish medical journal, 2019
Clinical question Recent 15-year updates of sigmoidoscopy screening trials provide new evidence on the effectiveness of colorectal cancer screening. Prompted by the new evidence, we asked: “Does colorectal cancer screening make an important difference to
L. Helsingen   +20 more
semanticscholar   +1 more source

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