Chemoprophylaxis in colorectal cancer: Current concepts and a practical algorithm for use [PDF]
Colorectal cancer (CRC) is the second most common lethal cancer in the Western world. There is a 10 to 20 years lead time from normal mucosa to carcinoma which offers a window of opportunity to modify and prevent the outcome of CRC, with its incipient ...
Chan, P +4 more
core +1 more source
Potential red-flag identification of colorectal adenomas with wide-field fluorescence molecular endoscopy [PDF]
Adenoma miss rates in colonoscopy are unacceptably high, especially for sessile serrated adenomas / polyps (SSA/Ps) and in high-risk populations, such as patients with Lynch syndrome.
Allende, P.B.G. (Pilar Beatriz Garcia) +14 more
core +2 more sources
Stromal Fibroblasts in Digestive Cancer [PDF]
The normal gastrointestinal stroma consists of extra-cellular matrix and a community of stromal cells including fibroblasts, myofibroblasts, smooth muscle cells, pericytes, endothelium and inflammatory cells.
Daniel L. Worthley +93 more
core +1 more source
Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening [PDF]
Colonoscopy and fecal immunochemical testing (FIT) are accepted strategies for colorectal-cancer screening in the average-risk population. METHODS: In this randomized, controlled trial involving asymptomatic adults 50 to 69 years of age, we compared one ...
Alonso-Abreu, Inmaculada +8 more
core +2 more sources
A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine. [PDF]
Primary adenocarcinoma of the anal canal is a rare and aggressive gastrointestinal disease with unclear pathogenesis. Because of its rarity, no clear clinical practice guideline has been defined and a targeted therapeutic armamentarium has yet to be ...
A Purkayastha +72 more
core +1 more source
A hidden Markov model-based algorithm for identifying tumour subtype using array CGH data [PDF]
Background The recent advancement in array CGH (aCGH) research has significantly improved tumor identification using DNA copy number data. A number of unsupervised learning methods have been proposed for clustering aCGH samples.
Ke Zhang +5 more
core +1 more source
Tumores malignos sincrônicos de cólon e reto. [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Silva, Marisa Helena da
core
Nucleic acid technology and infectious diseases [PDF]
The past decade has witnessed an explosion in the knowledge of microbial genetics, pathogenesis, and antimicrobial resistance as a result of advances in molecular technology.
Luk, WK, Wong, SSY, Woo, PCY, Yuen, KY
core
Immunohistochemical Detection of DNA Mismatch Repair Proteins Abnormalities in Sudanese Colorectal Cancer Patients [PDF]
Zakout, Yosef Mohamed
core +2 more sources
Clinicopathological and genotypic characteristics of colorectal cancer patients carrying a germline MUTYH mutation. [PDF]
Guzelis I +3 more
europepmc +1 more source

