Results 51 to 60 of about 7,899 (110)

Germline Cancer Susceptibility Variants in Patients With Uveal Melanoma

Pigment Cell &Melanoma Research, Volume 38, Issue 5, September 2025.
Germline exome sequencing of 106 Finnish patients with UM, considered at higher risk for genetic cancer predisposition, identified pathogenic or likely pathogenic variants associated with varying risk of malignancies in 16 patients (15%). Six patients (6%) carried multiple variants and had a median diagnosis age of 51, compared to 60 in the full cohort
Pauliina E. Repo, Eveliina Jakkula, Juho Hiltunen, Heidi Putkuri, Aleksandra Staskiewicz‐Tuikkanen, Reetta‐Stiina Järvinen, Martin Täll, Virpi Raivio, Rana'a T. Al‐Jamal, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Screening for colorectal cancer

CA: A Cancer Journal for Clinicians, Volume 76, Issue 3, May/June 2026.
wiley   +1 more source

Pancreatic Neuroendocrine Tumor in Lynch Syndrome: Expanding the Tumor Spectrum of Mismatch Repair Deficiency. [PDF]

Cureus
Mudupula Vemula SS, Sanka S, Natarajan V, Varghese MT, Isaac D.   +4 more
europepmc   +1 more source

Clinicopathological and genotypic characteristics of colorectal cancer patients carrying a germline MUTYH mutation. [PDF]

Rev Assoc Med Bras (1992)
Guzelis I, Gasimli R, Subaşıoğlu A, Sari A.   +3 more
europepmc   +1 more source

Lung adenocarcinoma and colorectal cancer as double primary malignancies reveal lynch syndrome: a case report of germline MLH1 mutation with response to immunotherapy and familial aggregation. [PDF]

Front Immunol
Wang M, Xue H, Hong J, Liu Q, Hu K, Shu C, Wang J, Long Y, Han Y, Yang X, Lu J.   +10 more
europepmc   +1 more source

WGS identifies Lynch syndrome (LS) patients and uncovers a large family with MSH2-related LS in Southern Thailand. [PDF]

PLoS One
Wanitsuwan W, Kanjanapradit K, Jearanai S, Suphasynth Y, Supaattagorn P, Vijasika S, Wanram S, Ngamphiw C, Nakhonsri V, Tongsima S, Satsue P, Sangkeaw N, Horpaopan S.   +12 more
europepmc   +1 more source

The Vital Role of Family Physicians in the Screening and Early Detection of Lynch Syndrome: A Case Report. [PDF]

Cureus
Campelos J, Gomes M, Campos A, Cardoso M, Lopes M.   +4 more
europepmc   +1 more source

Laparoscopic-assisted vs open surgery for synchronous colorectal cancer: a retrospective cohort study of short-term and long-term outcomes. [PDF]

BMC Gastroenterol
Liang J, Chen W, Yang J, Huang M, Wang H.   +4 more
europepmc   +1 more source

Double Trouble: EPCAM Exon 9 Deletion in Lynch Syndrome Leading to Dual Primary Tumors. [PDF]

Cureus
Kalfoutzou A, Rapti C, Almpanis Z, Bagiokou E, Kalakos N, Lagopoulou V, Kolintzikis V, Oikonomakis A, Chaleplidis N, Ramfidis V.   +9 more
europepmc   +1 more source

Constitutional epimutations in LTBP4, a component of the TGF-β signaling, and in BRCA1, as potential drivers of early-onset colorectal cancer. [PDF]

Clin Epigenetics
Terradas M, Mur P, Morón-Duran FD, Mengod P, Löffler CML, Helderman NC, Terlouw D, Sanjuán X, Bousquets-Muñoz P, Viana-Errasti J, Puente XS, Capellá G, Nielsen M, van Wezel T, Kather JN, Lázaro C, Moreno V, Valle L.   +17 more
europepmc   +1 more source