Results 31 to 40 of about 9,869 (156)
Hereditary ovarian cancer [PDF]
, 2009 Apoptosis is a form of cell death that permits the removal of damaged, senescent or unwanted cells in multicellular organisms, without damage to the cellular microenvironment.
BAZAN, Viviana +5 more
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Molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome)
Revista de la Facultad de Medicina, 2016 Lynch syndrome is the most common cause of inherited colorectal cancer, totaling 5 to 8% of all the cases with high susceptibility to this type of cancer and extracolonic cancer.
David Serrano, Clara Eugenia Arteaga
doaj +1 more source
Dermatology Research and Practice, 2010 Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS).
Michael C. Lynch, Bryan E. Anderson
doaj +1 more source
World Journal of Surgical Oncology, 2009 Background MLH1 is one of six known genes responsible for DNA mismatch repair (MMR), whose inactivation leads to HNPCC. It is important to develop genotype-phenotype correlations for HNPCC, as is being done for other hereditary cancer syndromes, in order
Yee Herman +6 more
doaj +1 more source
Systematic Review: An Update on the Spectrum of Urological Malignancies in Lynch Syndrome
Bladder Cancer, 2018 Background: Lynch syndrome is an autosomal dominant disorder that predisposes individuals affected to certain malignancies. Colon and endometrial cancers are the malignancies most highly associated with Lynch syndrome.
Dora Huang +3 more
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Pancreatic Cancer in Lynch Syndrome Patients [PDF]
, 2017 Although colorectal cancer (CRC) is the most common cancer type in Lynch syndrome (LS) families, patients have also increased lifetime risk of other types of tumors.
Bujanda Fernández de Pierola, Luis +1 more
core +4 more sources
Generational Expression of Muir-Torre Syndrome in a Canadian Family
Case Reports in Dermatological Medicine, 2016 Muir-Torre syndrome (MTS) is a rare autosomal dominant inherited genodermatosis that is considered to be a phenotypic subtype of hereditary nonpolyposis colorectal cancer (HNPCC), commonly referred to as Lynch syndrome. We describe the clinical course of
Kaitlin Alexandra Vanderbeck +2 more
doaj +1 more source
Metastatic rectal cancer to papillary thyroid carcinoma: a case report and review of literature
BMC Gastroenterology, 2020 Background Tumor-to-tumor metastasis is a rare event. Rectal cancer to primary thyroid neoplasm metastasis is extremely rare. Herein, we reported a case of metastatic rectal adenocarcinoma to a papillary thyroid carcinoma.
Min Luo +3 more
doaj +1 more source
A model-based assessment of the cost-utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients. [PDF]
, 2015 This is a freely-available open access publication. Please cite the published version which is available via the DOI link in this record.BACKGROUND: Lynch syndrome is an autosomal dominant cancer predisposition syndrome caused by mutations in the DNA ...
Coelho, H +7 more
core +2 more sources
Clinicopathologic and Molecular Profiles of Microsatellite Unstable Barrett Esophagus-associated Adenocarcinoma [PDF]
, 2014 Microsatellite instability (MSI) has been reported in various tumors, with colon cancer as the prototype. However, little is known about MSI in Barrett esophagus (BE)-associated adenocarcinoma.
Cohen, Cynthia +12 more
core +1 more source