Results 41 to 50 of about 9,869 (156)

Genetic changes of MLH1 and MSH2 genes could explain constant findings on microsatellite instability in intracranial meningioma [PDF]

open access: yes, 2017
Postreplicative mismatch repair safeguards the stability of our genome. The defects in its functioning will give rise to microsatellite instability. In this study, 50 meningiomas were investigated for microsatellite instability. Two major mismatch repair
Bukovac, Anja   +5 more
core   +1 more source

Postradiation Histiocytic Sarcoma in the Setting of Muir-Torre Syndrome

open access: yesCase Reports in Pathology, 2018
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is an autosomal dominant genetic disorder characterized by a predisposition towards colorectal carcinoma and other extracolonic neoplasms.
Erin Baumgartner   +6 more
doaj   +1 more source

Molecular pathology of colorectal cancer. [PDF]

open access: yes, 2014
Colorectal cancer (CRC) is one of the most intensively studied cancer types, partly because of its high prevalence but also because of the existence of its precursor lesions, tubular or villous adenomas, and more recently (sessile) serrated adenomas ...
Bosman, F., Yan, P.
core   +2 more sources

Frequency of hematologic and solid malignancies in the family history of 50 patients with acute myeloid leukemia - a single center analysis.

open access: yesPLoS ONE, 2019
Background and objectiveThe revised World Health Organization classification of 2016 for myeloid neoplasms and acute leukemia added a section of myeloid neoplasms with germline predisposition. The main objective of our study was to evaluate the frequency
Anne-Sophie Sandner   +5 more
doaj   +1 more source

Incidence and epidemiological features of synchronous and metachronous colorectal cancer

open access: yesJournal of Coloproctology, 2013
Introduction: patients with sporadic colorectal cancer or cases associated with syndromes are at risk of having synchronous or metachronous cancer. Although it is an important subject, Brazilian data on the subject are scarce.
Eduardo Brambilla   +4 more
doaj   +1 more source

Genetic pathways, prevention, and treatment of sporadic colorectal cancer [PDF]

open access: yes, 2014
Epithelial cancer of the colon and rectum, also known as colorectal cancer (CRC), results from a progressive accumulation of genetic and epigenetic alterations that lead to uncontrolled growth of colonocytes, the cells lining the colon and rectum. CRC is
Imperiale, Thomas F.   +4 more
core   +2 more sources

Detección de mutaciones de los genes hMLH1 y hMSH2 del sistema de reparación de malos apareamientos del ADN en familias colombianas sospechosas de cancer colorrectal no polipósico hereditario (síndrome de Lynch).

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2005
Introducción. El cáncer colorrectal es la segunda causa de morbilidad y mortalidad por cáncer en los países desarrollados. En Colombia es la quinta causa de muerte entre los diferentes cánceres.
Andrea Gómez   +11 more
doaj   +1 more source

Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience [PDF]

open access: yes, 2008
Background Adenocarcinoma of the small bowel is a relatively rare malignancy as compared to the other malignancies of the gastrointestinal tract. Nonspecific presentation and infrequent occurrence often leads to a delay in diagnosis and consequent poor ...
Kongkrit Chaiyasate   +4 more
core   +2 more sources

Duodenal Carcinoma from a Duodenal Diverticulum Mimicking Pancreatic Carcinoma [PDF]

open access: yes, 2012
An 81-year-old man was found to have a pancreatic head tumor on abdominal computed tomography (CT) performed during a follow-up visit for sigmoid colon cancer. The tumor had a diameter of 35mm on the CT scan and was diagnosed as pancreatic head carcinoma
Furukawa, Masashi   +5 more
core   +1 more source

Faecal haemoglobin can define risk of colorectal neoplasia at surveillance colonoscopy in patients at increased risk of colorectal cancer. [PDF]

open access: yes, 2020
Background: Quantitative faecal immunochemical tests measure faecal haemoglobin concentration (f-Hb), which increases in the presence of colorectal neoplasia.Objective: We examined the diagnostic accuracy of faecal immunochemical test (FIT)in patients at
Cleary, Shirley   +9 more
core   +2 more sources

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